ZINC & Copper - the importance inside the body

by Numerous experts

My desire is to provide several articles from those adroit in the subject. COPPER: the less talked about, and important trace mineral, the importance of Zinc, and when taking high Zinc, make sure you know the ratio of zinc to copper supplements. 

ZINC impairs RNA viruses ... Covid, Polio, etc.

Zn(2+) inhibits coronavirus and arterivirus RNA polymerase activity in vitro
​and zinc ionophores block the replication of these viruses in cell culture

Ralph Baric and other scientists knew in 2010 the "antidote"/treatments for the upcoming virus(es). He coauthored the discovery "Increasing the intracellular Zn(2+) concentration with zinc-ionophores like pyrithione (PT) can efficiently impair the replication of a variety of RNA viruses". Dr. Vladimir Zelenko based his effective protocol after watching the "MedCram Lecture 34 by Dr. Roger Seheult about the use of zinc and zinc ionophores. Zinc is an essential mineral for humans, and a little extra zinc is sometimes used to lessen the intensity of colds and sore throats. An ionophore is a chemical that opens the cell wall to allow minerals (ions) to enter.  ‘First do no harm’ Zinc is an over-the-counter supplement. Hydroxychloroquine (HCQ) is a reliable ionophore, and it has a well-established dosing regimen and safety profile."

Zinc ionophores "increase the intracellular concentration of Zinc ions causing significant biological effects. Review ionophores: HCQ, EGCG (a plant compound particularly prominent in green tea) and Quercetin (particularly in citrus fruits, apples, onions, parsley, sage, tea, and red wine. Olive oil, grapes, dark cherries, and dark berries such as blueberries, blackberries, and bilberries are also high in quercetin and other flavonoids.) "  

​"Excessive zinc supplementation can lead to a copper deficiency. That is because these two nutrients compete for absorption sites, and zinc preferentially binds for absorption." Copper supplementing is important when taking higher zinc.

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ZINC essential for life sustaining body functions!

ZINC: Roles in Pancreatic Physiology & Disease

NIH Published in final edited form as: Pancreatology. 2020 Sep 3;20(7):1413–1420. doi: 10.1016/j.pan.2020.08.016

"Zinc is an essential trace element. Deficiencies are frequently seen with gastrointestinal diseases, including chronic pancreatitis, nutritional deficiency, and reduced intestinal absorption. Additionally, reduced zinc levels have been linked to cellular changes associated with acute pancreatitis such as enhanced inflammation with increased macrophage activation and production of inflammatory cytokines such as IL-1β, impaired autophagy, and modulation of calcium homeostasis. Preliminary data suggest that zinc deficiency may lead to pancreatic injury in animal models."
​Link to read the full article 

(A) Model of acute pancreatitis in with normal (Sufficiency) zinc levels; (B) Potential effects of zinc depletion (Deficiency) on acinar cell pancreatitis responses. HMGB1 = High mobility group box 1 protein; nDNA = normal DNA; mtDNA = mitochondrial DNA; Hsp = heat shock protein; Ab = antibody; DAMPs = damage-associated molecular patterns; TRPV4 = transient receptor potential cation channel subfamily V Member 4; PLA2 = phospholipase A2; Piezo1 = piezo type mechanosensitive ion channel component 1; Orai1 = calcium release-activated calcium modulator 1; RER = rough endoplasmic reticulum; SER = smooth endoplasmic reticulum; Ryr = ryanodine receptor; PMCA4b = plasma membrane calcium-transporting ATPase 4; NLRP3 = NLR family pyrin domain containing 3; Zip8 = Zrt-Irt-like protein 8; GPR39 = G-protein coupled receptor 39.

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Ron Reece @Mujhunter
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I believe that Ivermectin is effective against SARS-2 for it's RdRP binding/inhibition as EARLY treatment, and anti-inflammatory effects, as well as suppressing the Importin A/B interference that signals our interferon response with SARS-2. However, as an anti-parasitic (toxin) I wouldn't recommend it as a viable daily prophylactic. Just as I also wouldn't recommend Chemotherapy as a daily prophylaxis for cancer. Zinc is a natural mineral critical to our cellular activities, so maintaining ELEMENTAL Zinc sufficiency (RDA of 8-15 mg daily) and being prepared to temporarily increase that Zinc concentration intracellularly by use of a Zinc Ionophore (HCQ, Quinine, EGCG, Quercetin, Zinc Ascorbate(?).. etc is a FAR more preferable long term prophylaxis. Zinc deficiency in the global population is growing as the result of our mass agricultural practices that often do not replace it in the soils, or chelates it from plants we eat using Glyphostates. Zinc, as demonstrated by Gain of Function expert, Ralph Baric, and first implemented by Dr. Zev Zelenko, ALSO disrupts the RdRP replicase of RNA Viruses. As EARLY treatment (don't wait for PCR results), a combination of both the Zelenko Protocol and Ivermectin will likely be a very potent combination against all RNA viruses (if only for the RdRP inhibition). But for daily prophylactic use, I stick with RDA Zinc levels, and a moderate amount of natural Zinc Ionophore. I personally take 25mg Zinc Sulfate (25% elemental Zinc) and EGCG every day. Zinc is ALSO critical to the proper function of the p53 protein that binds damaged (cancerous) DNA and not having enough can increase the chances of tumor growth. p53 is also known as the "Guardian of the Genome".. It's that critical and it require Zinc to function properly. Zinc also is critical for over 300+ physiological functions. Despite how critical it is, too much of it (above RDA recommendations) can be toxic and chelate Copper and other vital minerals. You need just enough on a daily basis, and ready to temporarily increase it when exposed/infected with an RNA Virus, in combination with a potent Zinc Ionophore. It has Ralph Baric's Gold Standard "seal of approval" stamped on it. And THAT makes all the difference, (evil?) RNA Viral genius that he is. https://ncbi.nlm.nih.gov/pmc/articles/PMC2973827/

God's creation of finely tuned 'orchestra'

Zinc (Zn) Copper (Cu) and Iron (Fe)
​impact each other.  ​Source A     Source B     Source C

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Linus Pauling Institute
ZINC: "Taking large quantities of zinc (50 mg/day or more) over a period of weeks can interfere with copper bioavailability. High intake of zinc induces the intestinal synthesis of a copper-binding protein called metallothionein (see the article on Copper). Metallothionein traps copper within intestinal cells and prevents its systemic absorption (see Wilson’s disease).

• Long-term consumption of zinc in excess of the tolerable upper intake level (UL; 40 mg/day for adults) can result in copper deficiency. (More information)
• Supplementation with doses of zinc in excess of the UL is effective to reduce the duration of common cold symptoms. The use of zinc at daily doses of 50 to 180 mg for one to two weeks has not resulted in serious side effects. (More information)
• Current evidence suggests that supplemental zinc may be useful in the management of chronic conditions, such as age-related macular degeneration, diabetes mellitus, Wilson’s disease, and HIV/AIDS. (More information)
• Zinc bioavailability is relatively high in meat, eggs, and seafood; zinc is less bioavailable from whole grains and legumes due to their high content in phytate that inhibits zinc absorption. (More information)"

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COPPER essential for life sustaining body functions!

Mount Sinai "Copper is a mineral that is found throughout the body. It helps your body make red blood cells and keeps nerve cells and your immune system healthy. It also helps form collagen, a key part of bones and connective tissue. Copper may also act as an antioxidant, reducing free radicals that can damage cells and DNA. Copper helps the body absorb iron. Your body also needs copper to make energy."

Harvard Public Health
​"... (Copper) assist(s) various enzymes that produce energy for the body, break down and absorb iron, and build red blood cells, collagen, connective tissue, and brain neurotransmitters. Copper also supports normal brain development and immune functions, and is a component of superoxide dismutase, an antioxidant enzyme that dismantles harmful oxygen “free radicals.” Copper is absorbed in the small intestine and found mainly in bones and muscle tissue."

A few foods high in copper

Liver                     Oysters
Spirulina             Salmon
Nuts & Seeds      Green Leafy 
​Shiitake Mushrooms
​Dark Chocolate (Cocoa) NOT sweetened
Link of many foods and mg/servings

Dr. Shiva The Power of Copper to fight virus, bacteria on contact

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"Researchers found that copper-based alloy surfaces have the ability to destroy a wide range of microbes and bacteria relatively rapidly - often within two hours or less. Several studies found that if touch surfaces are made with copper-based alloys, the reduced transmission of disease-causing bacteria can reduce patient infections in hospitals by as much as 58%."

Copper has even been shown to be very effective at exterminating the much-dreaded hospital ‘superbug’ MRSA. In tests sponsored by the Copper Development Association, a grouping of 100 million MSRA bacteria atrophied and died in a just 90 minutes, when placed on a copper surface at room temperature. The same study found that the same number of MSRA bacteria on both steel and aluminium surfaces actually increased over time. On looking at these figures, many scientists have concluded that the installation of copper-based fixtures such as taps, light switches, door handles, door knobs, pull handles, and push plates in areas such as hospitals could save thousands of lives each year.
Professor Bill Keevil, head of the microbiology group at Southampton University, added his voice to the growing scientific consensus behind this by advocating the use of Copper and Brass door furniture, fixtures and fittings in public places and on public transport, as they could dramatically cut the threat posed by superbugs.
In research published in the journal Molecular Genetics of Bacteria Professor Keevil wrote: “There are a lot of bugs on our hands that we are spreading around by touching surfaces. In a public building or mass transport, surfaces cannot be cleaned for long periods of time… Until relatively recently brass was a relatively commonly used surface. On stainless steel surfaces these bacteria can survive for weeks, but on copper surfaces they die within minutes… We live in this new world of stainless steel and plastic, but perhaps we should go back to using brass more instead.”
In addition to direct contact killing of bacteria and harmful microbes, amazingly Copper surfaces have been found to exude an antimicrobial 'halo' effect on surrounding non-copper surfaces. Research in the intensive care unit a Hospital in Greece found that other surfaces up to 50 centimetres from copper surfaces experienced 70% microbial reduction, compared to the same surfaces with no proximity to copper-based materials. The ‘Halo’ effect was also observed in trials at a U.S. clinic in 2010. This amazing effect demonstrates just how powerful copper is as a weapon against bacteria."  www.morehandles.co.uk