Nitric oxide (NO) - why you should know about this most important gas, created in our bodies10/5/2023 by Rose RohloffContribution by Dr John Marx, MB BS, BSc.(Hons) Nitrate and Nitrite in Health and Disease  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6147587/ Discovery of NONitric Oxide (NO) was discovered through research in the 1970s-80s Robert F. Furchgott, Louis J. Ignarro, and Ferid Murad shared the Noble Prize in 1998 for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular system  NO and COVID/Sars CoV 2Effects of Adding L-arginine orally to standard therapy in patients with Covid-19; Randomized, double-blind, placebo-controlled, parallel-group trial. Sept 09, 2021 Giuseppe Fiorentino 1 Antonietta Coppola 1 Raffaele Izzo Anna Annunziata Mariano Bernardo Angela Lombardi Show all authors "Strikingly, patients treated with L-arginine exhibited a significantly reduced in-hospital stay vs placebo, with a median (interquartile range 25th,75th percentile) of 46 days (45,46) in the placebo group vs 25 days (21,26) in the L-arginine group (p < 0.0001); these findings were also confirmed after adjusting for potential confounders including age, duration of symptoms, comorbidities, D-dimer, as well as antiviral and anticoagulant treatments." Read full Lancet article  Bioflex, maker of Photo Bio Modulation (PBM) "red light" therapies What does NO do in the body?I like to think of NO as a great conductor of the most vital, life-sustaining functions in the body. - neuro communication - cardiac function - proper clotting - ovaries - hypothalmus and pituitary functions as well as others.
"Nitric oxide, having a free electron, is a free radical, making it an interesting signaling molecule. NO functions as a neurotransmitter, a macrophage-derived host-defense molecule, inhibits platelet aggregation and endothelium adhesion molecule expression, is an antioxidant, and is a potent vasodilator [1,2]. Nitric oxide is an endothelium-derived relaxing factor (EDRF)...Due to its many roles, loss of NO bioactivity contributes to disease in a variety of conditions including hemolytic anemias like sickle cell disease [8], transfusion of older blood [9], and endothelial dysfunction that occurs in pathological conditions like metabolic syndrome [10]" NIH article
... Deep dives into NO are needed for an individual's health - educate yourself, and then discuss with clinicians. NO and strokes/CVA, American Heart Association Journal, December 2011 AHA Journals, ahajournals.org › doi › 10.1161 › circresaha.111.253419 Inhalation of Nitric Oxide Prevents Ischemic Brain Damage in Experimental Stroke by Selective Dilatation of Collateral Arterioles | Circulation Research These findings were validated in ... Inhaled nitric oxide thus may provide a completely novel strategy to improve penumbral blood flow and neuronal survival in stroke or other ischemic Things that hinder NOThe following are only a few tangible influences that impact NO production in the body:
 How many drugs are prescribed when there are simple natural remedies available?  by Dr John Marx, MB BS, BSc.(Hons) Are we only beginning to understand this amazing gas, and the miraculous function of the body?
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