by Rose Rohloff
Each person, in each individual situation, needs evaluation regarding whether a medication is necessary or not, and safe/appropriate. It is up to that person to make decisions with their clinician, not by the medical staff - or worse, an AI computer - without full data. Before a clinician gives a drug or writes a prescription for someone, the following questions should be answered to obtain true informed consent or refusal. Informed Consent1- What is the drug classification, the exact mechanism of action = what exactly is it doing in my body or the body of my loved one? 2- Was this researched, efficacy tested with chimera = baby organs cut out while they're alive, to be put into mice for drug/shot testing which is violating our religious right to not participate with child sacrifice/anything that is an abomination to God? [Read my blog Modern Child Sacrificing Continues] 3- List all side effects and contraindications, including immediate, short AND long-term. 4- List all causations to my condition or that of my loved one, and how have they been addressed or ruled out, including: lifestyle changes; diet; possible heavy metal/chemical exposure; parasites; imbalance of micronutrients, especially copper, iodine, selenium, manganese, magnesium, zinc, Iron (Fe2 vs Fe3); Vitamins D, Bs ... etc. 5- What are all the natural alternatives? 6- What are the latest independent studies not from pharmaceutical companies or those on the payroll or in bed with Pharma? 7- Where are all the primary Pharma and independent studies to show that the condition is not from the Covid Spike Protein, known to not be excreted by the body, and/or other shots or drugs? If situations involve your body, your health, your SOUL integrity, no true clinician upholding an oath to do no harm would get defensive by discussing any of the above. Time to DecideA very important element not discussed, and often violated by hospitals and MDs is the concept of time to make a decision, and giving of all necessary information listed above. Emergent: something must be done within an hour (< 1 hour) to prevent mortality (death) or morbidity (severe injury). An example is an aneurysm that is leaking or about to burst, etc. Urgent: something must be done within < 24 hours to prevent mortality (death) or morbidity (severe injury). An example is a severe break that needs setting, or excessive bleeding, etc. Elective/Selective/NonEmergent/NonUrgent: As the list refers to, nothing imminent and people can take days/weeks to research to make good decisions for themselves after becoming fully informed. Examples include joint replacements, general maintenance medications, 'vaccines" and other shots. Informed RefusalIn a previous blog, I reviewed being proactive with a document listing any and all things already fully researched with informed, established refusal. Read with this link. 
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by Rose RohloffToo often, media or public figures convolute issues with complex over/misinformation. Below is a high-level, brief overview to hopefully simplify the issue of COVID-19/SARS-CoV-2. Timeline - the Tale of Ralph Baric
Let's take a break to clarify definitions ...
Humanized Mice defined as "mice engrafted with functional human cells or tissues ... in various areas of biomedical research." Link Basically, government & pharma buying fresh baby tissue, stem cells or organs to put into or on an animal to test shots and drugs. Wait, in 2010 he co-authored how these viruses are stopped, so there was no need for a vaccine, the research ... correct?  https://pubmed.ncbi.nlm.nih.gov/21079686/ And exactly who funded it ... ?  EcoHealth Alliance, DARPA document In review, GOF are "experiments that modify pathogens—such as viruses—to enhance their transmissibility, virulence". Taking a spike protein that one engineers, and inserting into the backbone of an already engineered virus is experimenting with a pathogen to make it more virulent, correct?
Along with many other conspirators-organizations ... Freedom of Information (FOI) documents on origins of Covid-19, gain-of-function research and biolabs, including but not limited to many Universities, US Gov, China, etc. Link to read the documents Included is an email from one scientist to another, "Peter (head of EcoHealth Alliance) and his crazy ideas. This is so risky, how exciting." Hold on, what exactly is an ACE2 receptor, |
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When evaluating for causes, people often forget to look at the whole picture, look at the combination of issues versus isolated reasons. Continue reading for examples.
Heavy Metals - PFAS Chemicals
A lot of literature is now easily available regarding heavy metal toxicity from shots (aka vaccines), chemtrails, sprays on food, cooking pans, teeth fillings, etc.
Many conditions, whether neuro or organ impairment, and mental issues, may be attributed to heavy metals. Only a few examples:
Many conditions, whether neuro or organ impairment, and mental issues, may be attributed to heavy metals. Only a few examples:
- Aluminum Aluminium in brain tissue in familial Alzheimer’s disease, 2017
- Cadmium Exposure to cadmium and its impacts on human health: A short review, 2025
- Mercury Mercury Exposure and Heart Diseases, 2017
- Cobalt Cobalt poisoning "is a well-documented complication associated with metal-on-metal hip implants, primarily due to the release of cobalt and chromium ions. "Absorbing a large amount of cobalt over longer periods of time can lead to serious health problems, such as:
- Cardiomyopathy (a problem where your heart becomes big and floppy and has problems pumping blood)
- Deafness
- Nerve problems
- Ringing in the ears (tinnitus)
- Thickening of the blood
- Thyroid problems
- Vision problems
A significant amount of literature also addresses water table contamination and issues related to parasites.
Disease or Symptom: Effect is Symptom while Cause is the Problem
For this writing, only a few of the many examples are covered. The main micronutrients of iodine, selenium, magnesium, manganese, and copper, along with essential vitamins, are a good focus.
Atrial fibrillation (Afib) - condition ... or symptom?
- Selenium deficiency is associated with new-onset atrial fibrillation in PREVEND: a prospective general population cohort, 2022
- Micronutrient deficiencies and new-onset atrial fibrillation in a community-based cohort, 2025
- "Selenium deficiency is associated with a significantly increased risk of new-onset atrial fibrillation (AFib), particularly in non-smokers, according to a large prospective cohort study (PREVEND) involving over 5,400 participants. After adjusting for other risk factors, individuals with selenium deficiency had a 69% higher risk of developing AFib (HR 1.69, p = 0.020)."
- Low magnesium levels have been implicated as a risk factor for the development of atrial fibrillation (AF), 2013
- Nitric Oxide (NO) Hope for Patients With Atrial Fibrillation, 2002 "NO is a critical signaling molecule with diverse physiological roles across multiple systems, including regulation of clotting, ovarian function, cardiac activity, and neural communication."
Cancer - condition ... or symptom?
White blood cells/our immune system is designed to "eat up" or destroy and eliminate foreign invaders, including cancer cells. "Macrophages can eliminate cancer cells through multiple mechanisms, primarily by phagocytosis, direct cytotoxicity, and by orchestrating broader anti-tumor immune responses.
White blood cells/our immune system is designed to "eat up" or destroy and eliminate foreign invaders, including cancer cells. "Macrophages can eliminate cancer cells through multiple mechanisms, primarily by phagocytosis, direct cytotoxicity, and by orchestrating broader anti-tumor immune responses.
- CDC researchers link cancer cells from parasite to human tumors, Nov 4, 2015
1951 Confidential CIA document
X account Concerned Citizen
- PFOA, PFOS, and Related PFAS Chemicals, American Cancer Society
- "Both PFOA & PFOS areclassified as possible human carcinogens by the International Agency for Research on Cancer (IARC), PFOA upgraded in 2023"
What is the downside of assessing for parasites, white blood cells-immune system dysfunction, heavy metal toxicity, forever chemicals, etc.?
Endocrine disorders - condition ... or symptom?
Thyroid - Role of iodine, selenium and other micronutrients in thyroid function and disorders, 2009
Thyroid - Role of iodine, selenium and other micronutrients in thyroid function and disorders, 2009
- Copper toxicity "is strongly linked to nervousness and anxiety, particularly through its impact on neurotransmitter balance and thyroid function. Excess copper can disrupt the copper-zinc ratio, which is critical for neurological health. When copper levels are high and zinc low—common in copper toxicity—this imbalance can lead to overstimulation of the central nervous system, resulting in anxiety, panic attacks, depression, and attention deficits."
- Vitamin C: Essential for cortisol production in the adrenal glands; deficiency impairs the stress response and contributes to adrenal fatigue.
B Vitamins (especially B5, B6, B12, B2, B9): Critical for energy metabolism, neurotransmitter synthesis, and supporting the nervous system under stress; low levels impair HPA axis function and increase fatigue.
Magnesium: Required for proper HPA axis regulation; deficiency amplifies stress response, increases anxiety, and disrupts cortisol balance.
Vitamin D: Deficiency is linked to increased cortisol production and worsened adrenal insufficiency; also vital for immune and hormonal health.
Omega-3 Fatty Acids: Low levels are associated with elevated CRH and cortisol, chronic inflammation, and impaired stress resilience.
Zinc and Iron: Deficiencies can disrupt hormone regulation and contribute to HPA axis dysregulation, with iron deficiency potentially affecting hypothalamic function.
DHEA: Often low in HPA dysfunction; a precursor to sex hormones and a neurosteroid that supports stress resilience. - Tatoos: "Copper is one of the most prevalent heavy metals found in tattoo inks, with concentrations reaching up to 25,701 mg/kg in some products. A 2025 study on EU-market inks found that copper was the most concerning metal for non-cancer health risks, with up to 85.4% of products showing unacceptable exposure levels (MoS <100) under realistic tattooing scenarios."
- Vaping/e-cigarettes: Vaping exposes users to harmful levels of heavy metals, including lead, nickel, chromium, cadmium, arsenic, and uranium, which can accumulate in the body and pose serious health risks, especially for youth. Evidence from the Korea National Health and Nutrition Examination Survey, 2025.
Manganese is a mineral element that is both nutritionally essential and potentially toxic. The derivation of its name from the Greek word for magic remains appropriate, because scientists are still working to understand the diverse effects of manganese deficiency and manganese toxicity.
The bottom line of this article, the underlying 'why' or 'how' is the cause/the problem, and everything stemming from it is a symptom of the issue. It is up to each individual to investigate what is going on in their own body.
* unless cited, facts listed above are AI generated answers from multiple sources.
* unless cited, facts listed above are AI generated answers from multiple sources.
Why Do Cells 'Turning Off' Underlie So Many Chronic Diseases? Understanding the Cell Danger Response is critical for treating spike protein injuries and many other complex illnesses.
A Midwestern Doctor - The Forgotten Side of Medicine, Feb 2, 2026
https://www.midwesterndoctor.com/p/why-do-cells-turning-off-underlie
Regenerative Medicine and The Cell Danger Response
How locally resolving the cell danger response allows chronically impaired tissues to heal and resume their normal function.
A Midwestern Doctor - The Forgotten Side of Medicine, Feb 9, 2026
https://open.substack.com/pub/amidwesterndoctor/p/regenerative-medicine-and-the-cell-6c5?redirect=app-store
by Rose Rohloff
Child sacrificing to evil entities has moved from alters to labs and clinics.
Vaccines
 | Michigan - full 9-hour deposition/(confession) https://www.youtube.com/watch?v=DFTsd042M3o "Aborted fetal tissues are used in vaccines. Vaccines have been experimentally tested on orphans and on mental handicapped children. Experimental tests on babies from mothers in prisons. Experimental tests on 1 million people in then colonial Belgian Congo." |
'Babies Have To Remain Alive For Organs To Be Harvested In Vaccine (plus ALL DRUG) Development Experiments.' Aaron Siri says, 'You Can't Grow Viruses Using Dead Organ Tissue, They Have To Be Born Alive ... Dr. Stanley Plotkin Admits To All Under Oath ... Unborn Babies Are Alive At Tissue Extraction' ... Dr. Plotkin gladly admits, without remorse, to Lawyer Aaron Siri, that he accepts human sacrifice as a normal, acceptable consequence in order to further science' as he is 1st & foremost a scientist & practicing Atheist. Former Vaccine Researcher & Biologist Pamela Acker has stated, "The babies are alive when the researchers start extracting the tissue. Their hearts are still beating & they're not given any anesthetic because that would contaminate the organs being harvested that need to be alive, pure & free of toxins.' According to expert Dr. Theresa Deisher, PhD, 'Babies are born alive from five to six months old, with beating hearts cut out without anesthesia for research purposes. Researchers also cut through live babies' faces to collect brain tissue.'"
"Stanley Alan Plotkin is an American physician & vaccinologist renowned for his pivotal role in developing several critical vaccines. Born and raised in New York City, he attended The Bronx High School of Science, where at the age of 15, he was inspired by the books Arrowsmith by Sinclair Lewis and Microbe Hunters by Paul de Kruif to pursue a career in medicine and research. He earned his bachelor's degree from New York University in 1952 and his MD from SUNY Downstate Medical Center in 1956. Plotkin began his research career at the Wistar Institute in Philadelphia in the 1960s, where he played a key role in developing the rubella vaccine using the RA 27/3 strain of the virus, grown on the WI-38 fetal-derived human cell line ..." AI-generated answer from multiple sources.
Pharma Drugs & Gain-of-function (GOF) Gene Altering
Chimeric = Humanized Mice:
Humanized liver mouse models are increasingly being used in preclinical trials and have allowed for groundbreaking in-vivo research to evaluate everything from human-specific drug toxicity and efficacy to gene therapies. Hera Biolabs
Humanized mice, created by introducing human stem cells into mouse embryos. Human cells have been injected into the amniotic fluid of pregnant mice, where they migrated to fetal organs such as the intestines, liver, and brain, demonstrating a promising technique for creating humanized mouse models. AI generated from multiple sources. https://med.stanford.edu/news/all-news/2012/10/mice-with-humanized-livers-improve-early-drug-testing-scientist-show.html
Humanized liver mouse models are increasingly being used in preclinical trials and have allowed for groundbreaking in-vivo research to evaluate everything from human-specific drug toxicity and efficacy to gene therapies. Hera Biolabs
Humanized mice, created by introducing human stem cells into mouse embryos. Human cells have been injected into the amniotic fluid of pregnant mice, where they migrated to fetal organs such as the intestines, liver, and brain, demonstrating a promising technique for creating humanized mouse models. AI generated from multiple sources. https://med.stanford.edu/news/all-news/2012/10/mice-with-humanized-livers-improve-early-drug-testing-scientist-show.html
Harma: Drugs & Vaccines use Humanized Mice as a Valuable Pre-Clinical Model
- For Cancer Immunotherapy Research: https://pmc.ncbi.nlm.nih.gov/articles/PMC8636317/
- For Cardiac Research: A humanized monoclonal antibody targeting an ectonucleotidase rescues cardiac metabolism and heart function after myocardial infarction. https://www.sciencedirect.com/science/article/pii/S2666379124005421
- For over-the-counter Antihistamines: Clemizole is a chemical compound originally developed as a first-generation antihistamine but is now being researched for its potential in treating other conditions, including Dravet syndrome, a rare form of epilepsy, as well as Hepatitis C.
- For Diabetes - Weight Loss: Ozempic, studies conducted on humanized mice have provided critical insights into how Ozempic (semaglutide) affects different bodily systems, going beyond its well-known weight loss effects.
- An exhaustive list of every drug tested on humanized mice is impossible to create - read below.
Planned Parenthood
SWORN VIDEO TESTIMONY DESCRIBES INFANTICIDE IN FETAL ORGAN HARVESTING
Read & Listen Planned Parenhood Procurment Managers
Read & Listen Planned Parenhood Procurment Managers
ABR https://www.centerformedicalprogress.org/human-capital/special-report-advanced-bioscience-resources/
When did this begin?
There is conflicting data on when this began - decades ago, according to AI searches:
"The first documented use of humanized mice for drug testing involved the evaluation of Clemizole, a drug being developed for Hepatitis C. Scientists used chimeric mice with humanized livers to study the drug's metabolism and interactions" Clemizole was first described in the scientific literature in 1952 and was discovered in the 1950s as a first-generation ..."
"The first reporting of humanized mouse models occurred in 1988, when three independent research groups successfully transplanted human hematopoietic cells into immunodeficient mice. Two of these studies utilized C.B17-SCID mice as recipients for either human peripheral blood or human fetal tissues." Humanized mice were first used in 1988 ... to model human immunodeficiency virus (HIV) infection and the human immune response to HIV. https://pmc.ncbi.nlm.nih.gov/articles/PMC7265413/
Stanford University scientists first used chimeric mice with humanized livers to predict human drug metabolism and drug-drug interactions in a landmark 2012 study.
The research, led by Gary Peltz, focused on clemizole, a drug in development for hepatitis C virus (HCV) infection. The team used TK-NOG mice—a model with livers largely replaced by human cells—to test how clemizole was metabolized and how it interacted with ritonavir, a known CYP3A4 inhibitor.
"The first documented use of humanized mice for drug testing involved the evaluation of Clemizole, a drug being developed for Hepatitis C. Scientists used chimeric mice with humanized livers to study the drug's metabolism and interactions" Clemizole was first described in the scientific literature in 1952 and was discovered in the 1950s as a first-generation ..."
"The first reporting of humanized mouse models occurred in 1988, when three independent research groups successfully transplanted human hematopoietic cells into immunodeficient mice. Two of these studies utilized C.B17-SCID mice as recipients for either human peripheral blood or human fetal tissues." Humanized mice were first used in 1988 ... to model human immunodeficiency virus (HIV) infection and the human immune response to HIV. https://pmc.ncbi.nlm.nih.gov/articles/PMC7265413/
Stanford University scientists first used chimeric mice with humanized livers to predict human drug metabolism and drug-drug interactions in a landmark 2012 study.
The research, led by Gary Peltz, focused on clemizole, a drug in development for hepatitis C virus (HCV) infection. The team used TK-NOG mice—a model with livers largely replaced by human cells—to test how clemizole was metabolized and how it interacted with ritonavir, a known CYP3A4 inhibitor.
1996 Flu Shot
US Government WITH Pharma Companies & Universities
FDA, NIH Buying Aborted Human Fetal Parts for Experiments link to read
Judicial Watch reveals that the U.S. Food and Drug Administration (FDA) has paid tens of thousands of taxpayer dollars to obtain human fetal tissue from the California-based “procurement” firm Advanced Bioscience Resources (ABR), undoubtedly supplied by abortion providers such as Planned Parenthood. According to the report, the fetal tissue was used in a sort of Frankenstein project to create “humanized mice” to test “biologic drug products.” To this day, research continues unimpeded.
E-mail dated September 27, 2012, Howard submitted an application to Larton for “tissue purchases” in the amount of $12,000. The contract reportedly requested tissue from an aborted fetus with a gestational age of 16 to 24 weeks and “One set of tissue (thymus/liver) approx. twice monthly.” Instructions stated that the tissues were to be shipped “fresh; on wet ice."
Judicial Watch reveals that the U.S. Food and Drug Administration (FDA) has paid tens of thousands of taxpayer dollars to obtain human fetal tissue from the California-based “procurement” firm Advanced Bioscience Resources (ABR), undoubtedly supplied by abortion providers such as Planned Parenthood. According to the report, the fetal tissue was used in a sort of Frankenstein project to create “humanized mice” to test “biologic drug products.” To this day, research continues unimpeded.
E-mail dated September 27, 2012, Howard submitted an application to Larton for “tissue purchases” in the amount of $12,000. The contract reportedly requested tissue from an aborted fetus with a gestational age of 16 to 24 weeks and “One set of tissue (thymus/liver) approx. twice monthly.” Instructions stated that the tissues were to be shipped “fresh; on wet ice."
Judicial Watch - Freedom of Information Act (FOIA) documents Link to read
NIH Fetal Tissue Use
"The National Institutes of Health (NIH) has specific requirements for research involving human fetal tissue obtained from elective abortions, including the procurement and use of fresh fetal organs for pharmaceutical and medical research purposes. As of September 25, 2019, NIH implemented updated requirements for grant applications and research and development (R&D) contracts proposing the use of human fetal tissue (HFT) ..." Multiple sources
"The National Institutes of Health (NIH) has specific requirements for research involving human fetal tissue obtained from elective abortions, including the procurement and use of fresh fetal organs for pharmaceutical and medical research purposes. As of September 25, 2019, NIH implemented updated requirements for grant applications and research and development (R&D) contracts proposing the use of human fetal tissue (HFT) ..." Multiple sources
Covid Bioweapon "vaccines" created with aborted cells/tissue/organs
Many people only view the HEK 293 cell line (derived from human embryonic kidney cells from an aborted baby in the 1970s: There is no statute of limitations on the issue), while ignoring the fresh tissue and organs being obtained for research of drugs: "vaccines", bioweapons, cancer drugs, "particularly the progagation of adenoviral-based ad retroviral-based vectors."
"Independent testing and expert testimony have confirmed the presence of residual DNA fragments in vials of mRNA Covid-19 shots, levels exceeding safety guidelines. Molecular biologist and cancer geneticist Phillip Buckhaults presented to a South Carolina Senate committee on September 12, 2023, stating that DNA pieces were present in leftover Pfizer/BioNTech vaccine vials and expressing concern about the potential for genome integration and cancer risks. Similarly, genomic expert Kevin McKernan reported finding DNA contamination in Pfizer and Moderna bivalent vaccine vials."
"J&J uses a modified adenovirus, Adenovirus 26, as the vector to deliver the genetic material encoding the SARS-CoV-2 spike protein to cells. The mRNA is packaged within a modified virus, known as a viral vector. The double viral vector approach involves using two viruses: the adenovirus vector and the SARS-CoV-2 virus. The adenovirus vector carries the genetic material encoding the SARS-CoV-2 spike protein, which is then expressed by the cells." From J&J website "... it was developed using a cell line originally derived from fetal tissue obtained from an elective abortion in the 1970s, known as the PER.C6 cell line."
Many people only view the HEK 293 cell line (derived from human embryonic kidney cells from an aborted baby in the 1970s: There is no statute of limitations on the issue), while ignoring the fresh tissue and organs being obtained for research of drugs: "vaccines", bioweapons, cancer drugs, "particularly the progagation of adenoviral-based ad retroviral-based vectors."
"Independent testing and expert testimony have confirmed the presence of residual DNA fragments in vials of mRNA Covid-19 shots, levels exceeding safety guidelines. Molecular biologist and cancer geneticist Phillip Buckhaults presented to a South Carolina Senate committee on September 12, 2023, stating that DNA pieces were present in leftover Pfizer/BioNTech vaccine vials and expressing concern about the potential for genome integration and cancer risks. Similarly, genomic expert Kevin McKernan reported finding DNA contamination in Pfizer and Moderna bivalent vaccine vials."
"J&J uses a modified adenovirus, Adenovirus 26, as the vector to deliver the genetic material encoding the SARS-CoV-2 spike protein to cells. The mRNA is packaged within a modified virus, known as a viral vector. The double viral vector approach involves using two viruses: the adenovirus vector and the SARS-CoV-2 virus. The adenovirus vector carries the genetic material encoding the SARS-CoV-2 spike protein, which is then expressed by the cells." From J&J website "... it was developed using a cell line originally derived from fetal tissue obtained from an elective abortion in the 1970s, known as the PER.C6 cell line."
An exhaustive list of every drug tested on humanized mice - aka dissected/sacrificed child organs or tissue put into animals aka abomination to God - is impossible to create because drug companies often keep preclinical data private. However, published scientific literature details numerous examples and classes of medicines tested in these models, particularly for research on immuno-oncology, infectious diseases, and drug metabolism.
Humanized mice are immunocompromised mice that have been engrafted with human genes, cells, or tissues, allowing researchers to study human-specific biological responses and disease processes.
Immuno-oncology.
Cancer immunotherapies (Chemo) are tested in humanized mouse models, which can be engineered with human immune cells and cancer cell lines (CDX) or patient-derived tumor tissue (PDX).
Humanized mice are essential for studying human-specific infectious agents and testing antiviral therapies.
Humanized mice can be engineered with human liver or metabolic enzymes to predict how the human body will process and break down a drug.
Humanized models are also used for research into a variety of other conditions:
Humanized mice are immunocompromised mice that have been engrafted with human genes, cells, or tissues, allowing researchers to study human-specific biological responses and disease processes.
Immuno-oncology.
Cancer immunotherapies (Chemo) are tested in humanized mouse models, which can be engineered with human immune cells and cancer cell lines (CDX) or patient-derived tumor tissue (PDX).
- Immune checkpoint inhibitors (ICIs): These block checkpoint proteins on T-cells to help the immune system fight cancer. Tested ICIs include:
- Nivolumab (anti-PD-1)
- Pembrolizumab (anti-PD-1)
- Atezolizumab (anti-PD-L1)
- Ipilimumab (anti-CTLA-4)
- Many ICI combination therapies, such as nivolumab and ipilimumab, have also been tested.
- Adoptive cell therapy (ACT): This involves using human immune cells to fight cancer, often genetically modified. Examples include:
- CAR-T cell therapy: Anti-CD19 and EGFR CAR-T therapies.
- CAR-NK cell therapy: Anti-GD2 CAR-NK therapy.
- TCR-T cell therapy: WT-1 TCR-T therapy.
- Oncolytic viruses: These are genetically engineered viruses that selectively target and kill cancer cells. Examples tested in humanized mice include:
- Herpes Simplex Virus (HSV-1 OV)
- Oncolytic Vaccinia Virus
- Cytokine manipulation: Studies have explored therapies using cytokines, like IL-12, to influence the immune response against tumors.
- Monoclonal and bispecific antibodies: Humanized FcRn mouse models are used to test antibodies, which can be engineered to have a longer half-life in humans. An example is the CD19xCD28 bispecific antibody, RG6333.
- Small molecule inhibitors: These are also tested in combination with immunotherapies, such as a CDK4/6 inhibitor plus anti-PD-1.
Humanized mice are essential for studying human-specific infectious agents and testing antiviral therapies.
- HIV/SIV: Humanized mice are used for testing antiretroviral therapies and their efficacy against both HIV and SIV infections. Drug combinations tested include:
- Emtricitabine (FTC), Bictegravir (BIC), and Tenofovir Alafenamide (TAF)
- Emtricitabine (FTC), Elvitegravir (EVG), and Tenofovir Disoproxil Fumarate (TDF)
- Hepatitis C: In 2012, a drug developed to fight hepatitis C was tested in mice with humanized livers.
- Dengue Virus (DENV): Humanized mice have been used to study DENV infection and test new therapeutics.
- Malaria: Researchers have studied Plasmodium falciparum infection and tested new therapeutics in humanized mice with both humanized livers and blood.
- Ebola Virus: Humanized mice were used to study the pathogenesis of Ebola virus infection and test new drugs.
Humanized mice can be engineered with human liver or metabolic enzymes to predict how the human body will process and break down a drug.
- Cytochrome P450 (CYP) enzymes: Mice engineered with human CYP enzymes (like CYP3A4) are used to test drug-drug interactions (DDIs). Drugs tested include:
- Triazolam
- Ritonavir
- Ketoconazole
- Midazolam
- Transport proteins: Models with human transport proteins, like MDR1 or OATP1B1, are used to study drug disposition and DDIs. Drugs tested include Digoxin and Atorvastatin.
- Chemotherapeutic drugs: Models with human hematopoietic systems are used to test the safety and lineage-specific toxicity of chemotherapy drugs like Oxilplatin, Topetecan, and Paclitaxel.
Humanized models are also used for research into a variety of other conditions:
- Autoimmune diseases: Models for conditions like psoriasis, atopic dermatitis, and rheumatoid arthritis are used to test drugs targeting specific human biomarkers.
- Metabolic disorders: Research into diabetes, obesity, and fatty liver disease uses humanized models targeting metabolic pathways.
- Neurological disorders: Models targeting pathways in neurological conditions like Alzheimer's and Parkinson's have been developed.
ZINC (Zn) & Copper (Cu) & Iron (Fe) - the gross importance in the body and disease process
9/15/2025
by Numerous experts
My desire is to provide several articles from those adroit in the subject. COPPER: the less talked about, and important trace mineral, the importance of Zinc, and when taking high Zinc, make sure you know the ratio of zinc to copper supplements.
ZINC impairs RNA viruses: Covid, Polio, Flu, etc. published 2010
Ralph Baric and other scientists knew in 2010 the "antidote"/treatment for the upcoming virus(es). He coauthored the discovery that "Increasing the intracellular Zn(2+) concentration with zinc-ionophores like pyrithione (PT) can efficiently impair the replication of a variety of RNA viruses". Dr. Vladimir Zelenko based his effective protocol after watching the "MedCram Lecture 34 by Dr. Roger Seheult about the use of zinc and zinc ionophores. Zinc is an essential mineral for humans, and a little extra zinc is sometimes used to lessen the intensity of colds and sore throats. An ionophore is a chemical that opens the cell wall to allow minerals (ions) to enter. ‘First do no harm’ Zinc is an over-the-counter supplement. Hydroxychloroquine (HCQ) is a reliable ionophore, and it has a well-established dosing regimen and safety profile."
Zinc ionophores "increase the intracellular concentration of Zinc ions causing significant biological effects. Review ionophores: HCQ, EGCG (a plant compound particularly prominent in green tea) and Quercetin (particularly in citrus fruits, apples, onions, parsley, sage, tea, and red wine. Olive oil, grapes, dark cherries, and dark berries such as blueberries, blackberries, and bilberries are also high in quercetin and other flavonoids.) "
 | "Excessive zinc supplementation can lead to a copper deficiency. That is because these two nutrients compete for absorption sites, and zinc preferentially binds for absorption." Copper supplementing is important when taking higher zinc. |
ZINC essential for life sustaining body functions!
Zn: Roles in Pancreatic Physiology & Disease
NIH Published in final edited form as: Pancreatology. 2020 Sep 3;20(7):1413–1420. doi: 10.1016/j.pan.2020.08.016
"Zinc is an essential trace element. Deficiencies are frequently seen with gastrointestinal diseases, including chronic pancreatitis, nutritional deficiency, and reduced intestinal absorption. Additionally, reduced zinc levels have been linked to cellular changes associated with acute pancreatitis such as enhanced inflammation with increased macrophage activation and production of inflammatory cytokines such as IL-1β, impaired autophagy, and modulation of calcium homeostasis. Preliminary data suggest that zinc deficiency may lead to pancreatic injury in animal models."
Link to read the full article
"Zinc is an essential trace element. Deficiencies are frequently seen with gastrointestinal diseases, including chronic pancreatitis, nutritional deficiency, and reduced intestinal absorption. Additionally, reduced zinc levels have been linked to cellular changes associated with acute pancreatitis such as enhanced inflammation with increased macrophage activation and production of inflammatory cytokines such as IL-1β, impaired autophagy, and modulation of calcium homeostasis. Preliminary data suggest that zinc deficiency may lead to pancreatic injury in animal models."
Link to read the full article
(A) Model of acute pancreatitis in with normal (Sufficiency) zinc levels; (B) Potential effects of zinc depletion (Deficiency) on acinar cell pancreatitis responses. HMGB1 = High mobility group box 1 protein; nDNA = normal DNA; mtDNA = mitochondrial DNA; Hsp = heat shock protein; Ab = antibody; DAMPs = damage-associated molecular patterns; TRPV4 = transient receptor potential cation channel subfamily V Member 4; PLA2 = phospholipase A2; Piezo1 = piezo type mechanosensitive ion channel component 1; Orai1 = calcium release-activated calcium modulator 1; RER = rough endoplasmic reticulum; SER = smooth endoplasmic reticulum; Ryr = ryanodine receptor; PMCA4b = plasma membrane calcium-transporting ATPase 4; NLRP3 = NLR family pyrin domain containing 3; Zip8 = Zrt-Irt-like protein 8; GPR39 = G-protein coupled receptor 39.
Ron Reece @Mujhunter | God's creation of finely tuned 'orchestra'Linus Pauling Institute ZINC: "Taking large quantities of zinc (50 mg/day or more) over a period of weeks can interfere with copper bioavailability. High intake of zinc induces the intestinal synthesis of a copper-binding protein called metallothionein (see the article on Copper). Metallothionein traps copper within intestinal cells and prevents its systemic absorption (see Wilson’s disease).
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COPPER essential for life sustaining body functions!
Mount Sinai "Copper is a mineral that is found throughout the body. It helps your body make red blood cells and keeps nerve cells and your immune system healthy. It also helps form collagen, a key part of bones and connective tissue. Copper may also act as an antioxidant, reducing free radicals that can damage cells and DNA. Copper helps the body absorb iron. Your body also needs copper to make energy."
Cu is an essential trace element critical for both the innate and adaptive immune systems. It supports immune function through multiple mechanisms: enhancing the activity of immune cells like neutrophils, macrophages, and natural killer (NK) cells; promoting the production and function of cytokines such as IL-2; and aiding in the proliferation and differentiation of T and B lymphocytes. Copper is also involved in the generation of reactive oxygen species (ROS) during the respiratory burst, which helps destroy pathogens"
| Harvard Public Health "... (Copper) assist(s) various enzymes that produce energy for the body, break down and absorb iron, and build red blood cells, collagen, connective tissue, and brain neurotransmitters. Copper also supports normal brain development and immune functions, and is a component of superoxide dismutase, an antioxidant enzyme that dismantles harmful oxygen “free radicals.” Copper is absorbed in the small intestine and found mainly in bones and muscle tissue." |  A few foods high in copper Liver Oysters Spirulina Salmon Nuts & Seeds Green Leafy Shiitake Mushrooms Dark Chocolate (Cocoa) NOT sweetened Link of many foods and mg/servings |
Cu deficiency impairs the function of ceruloplasmin (CP), a copper-dependent ferroxidase essential for iron efflux from cells. Without sufficient Cu, CP cannot properly oxidize ferrous iron (Fe²⁺) to ferric iron (Fe³⁺), which is required for iron binding to transferrin (Fe-TF) for transport in the blood. This leads to iron accumulation in cells, particularly in the liver and spleen, due to impaired iron release from storage sites like macrophages. As a result, free, unbound iron can increase in the bloodstream and tissues, contributing to oxidative stress and potential cellular damage."
"Many intracellular parasites and bacteria rely on unbound iron (Fe²⁺) for replication within host cells."
Dr. Shiva The Power of Copper to fight virus, bacteria on contact
 | "Researchers found that copper-based alloy surfaces have the ability to destroy a wide range of microbes and bacteria relatively rapidly - often within two hours or less. Several studies found that if touch surfaces are made with copper-based alloys, the reduced transmission of disease-causing bacteria can reduce patient infections in hospitals by as much as 58%." |
Copper has even been shown to be very effective at exterminating the much-dreaded hospital ‘superbug’ MRSA. In tests sponsored by the Copper Development Association, a grouping of 100 million MSRA bacteria atrophied and died in a just 90 minutes, when placed on a copper surface at room temperature. The same study found that the same number of MSRA bacteria on both steel and aluminium surfaces actually increased over time. On looking at these figures, many scientists have concluded that the installation of copper-based fixtures such as taps, light switches, door handles, door knobs, pull handles, and push plates in areas such as hospitals could save thousands of lives each year.
Professor Bill Keevil, head of the microbiology group at Southampton University, added his voice to the growing scientific consensus behind this by advocating the use of Copper and Brass door furniture, fixtures and fittings in public places and on public transport, as they could dramatically cut the threat posed by superbugs.
In research published in the journal Molecular Genetics of Bacteria Professor Keevil wrote: “There are a lot of bugs on our hands that we are spreading around by touching surfaces. In a public building or mass transport, surfaces cannot be cleaned for long periods of time… Until relatively recently brass was a relatively commonly used surface. On stainless steel surfaces these bacteria can survive for weeks, but on copper surfaces they die within minutes… We live in this new world of stainless steel and plastic, but perhaps we should go back to using brass more instead.”
In addition to direct contact killing of bacteria and harmful microbes, amazingly Copper surfaces have been found to exude an antimicrobial 'halo' effect on surrounding non-copper surfaces. Research in the intensive care unit a Hospital in Greece found that other surfaces up to 50 centimetres from copper surfaces experienced 70% microbial reduction, compared to the same surfaces with no proximity to copper-based materials. The ‘Halo’ effect was also observed in trials at a U.S. clinic in 2010. This amazing effect demonstrates just how powerful copper is as a weapon against bacteria." www.morehandles.co.uk
Professor Bill Keevil, head of the microbiology group at Southampton University, added his voice to the growing scientific consensus behind this by advocating the use of Copper and Brass door furniture, fixtures and fittings in public places and on public transport, as they could dramatically cut the threat posed by superbugs.
In research published in the journal Molecular Genetics of Bacteria Professor Keevil wrote: “There are a lot of bugs on our hands that we are spreading around by touching surfaces. In a public building or mass transport, surfaces cannot be cleaned for long periods of time… Until relatively recently brass was a relatively commonly used surface. On stainless steel surfaces these bacteria can survive for weeks, but on copper surfaces they die within minutes… We live in this new world of stainless steel and plastic, but perhaps we should go back to using brass more instead.”
In addition to direct contact killing of bacteria and harmful microbes, amazingly Copper surfaces have been found to exude an antimicrobial 'halo' effect on surrounding non-copper surfaces. Research in the intensive care unit a Hospital in Greece found that other surfaces up to 50 centimetres from copper surfaces experienced 70% microbial reduction, compared to the same surfaces with no proximity to copper-based materials. The ‘Halo’ effect was also observed in trials at a U.S. clinic in 2010. This amazing effect demonstrates just how powerful copper is as a weapon against bacteria." www.morehandles.co.uk
Iron (Fe) - there is not just one type in the body
Heme Iron
- Found in hemoglobin (oxygen transport in red blood cells), myoglobin (oxygen storage in muscles), and certain enzymes.
- Chemically exists as Fe²⁺ chelated within the heme structure (protoporphyrin IX).
- Absorbed efficiently (15–35%) and not regulated by body iron stores.
- Exists in two ionic forms:
- Ferrous iron (Fe²⁺): More bioavailable; absorbed directly via DMT1 transporter.
- Ferric iron (Fe³⁺): Must be reduced to Fe²⁺ (via duodenal cytochrome B reductase) before absorption.
- Found in plant foods, fortified foods, and animal products (in addition to heme iron).
- Absorption is highly regulated by body iron stores and influenced by dietary factors (e.g., vitamin C enhances absorption; phytic acid inhibits it).
- Ferritin: Primary intracellular storage form; iron is stored as Fe³⁺ in a protein shell.
- Transferrin: Plasma protein that binds and transports Fe³⁺ to tissues; regulates iron delivery.
- Hemosiderin: Insoluble, degraded form of ferritin; accumulates in excess iron storage.
- A small, reactive pool of free Fe²⁺ in cells involved in metabolic processes.
- Can generate reactive oxygen species (ROS) via the Fenton reaction; tightly regulated to prevent oxidative damage.
Unbound iron in the body, also known as free iron, is not typically measured directly in clinical practice."
"While unbound iron is theoretically part of the free fraction available for cellular use, it is not routinely measured."
The question for all doctors, "WHY is this not an essential component to evaluate along with Cu levels, especially if someone has an infection the body is not fighting off?
click on picture to read frull article https://www.frontiersin.org/research-topics/4986/role-of-iron-in-bacterial-pathogenesis/magazine
- The role of iron in the immune response to bacterial infection full article
- Copper plays a critical and multifaceted role in both innate and adaptive immunity, acting as an essential trace element for immune system development, function, and defense against pathogens.
- Copper regulates the host innate immune response against bacterial infection full article
Great lecture by Dr. Alphonso Monso, III - ND
Iron & Copper, The Greatest Dietary Lie of our Century! by Dr. Alphonso Monzo III click on photo to listen to lecture https://rumble.com/v3y9hrp-iron-and-copper-the-greatest-dietary-lie-of-our-century-dr-monzo-des-monies.html
by Rose Rohloff
Information collected from general, multiple AI common sources, unless otherwise denoted.
Perpetual Fight-or-Flight Stress
| The HPA axis is a neuroendocrine system that is part of the body's fight-or-flight reaction in times of stress or emergency = Hypothalamus, the Pituitary and the Adrenal glands. |  |
HPA Axis Dysfunction leads to constant biofeedback of hormone release, constant stress in perpetual fight-or-flight state with Cortisol staying high → Metabolic disorders, Blood glucose staying high → Mental health issues → Immunity shut down (cancers) → Heart rate accelerates and Blood pressure increases → etc.
Many people are not being diagnosed with this condition by MDs and are simply put on dangerous drugs (antidepressants/SSRIs/benzos) with issues not being addressed:
Many people are not being diagnosed with this condition by MDs and are simply put on dangerous drugs (antidepressants/SSRIs/benzos) with issues not being addressed:
- Spiritual Health: align with God, pray, give praise and thanks to God, and use healing frequencies to calm.
- Spike proteins and nanotech targeting organs (read https://www.delphinehc.com/blog/what-exactly-are-in-the-shots)
- Heavy metal toxicity: we are being sprayed with glyphosate, chemtrails with mercury, aluminum, cadmium, etc. etc. DETOX heavy metal to eliminate neurotoxins. "The primary heavy metal neurotoxins for humans are lead (Pb), mercury (Hg), arsenic (As), cadmium (Cd), and aluminum (Al)." (This list is not all-inclusive.)
- Micronutrient imbalances: Usually low but can be high (e.g. with Roundup chelating with copper in the soil, tattoos, etc.) Copper, Selenium, Iodine, Magnesium, and Manganese are examples and not being addressed by MDs. The perfect balance of the whole endocrine system is essential. When one hormone is messed with, it is a cascading effect.
- Virus or Parasite infections Link to read.
- Nitric Oxide (NO), glutamine/glutathione productions:
- NO regulates all of our essential body functions, including neurocommunication, heart, ovaries, etc ... "Nitric oxide (NO) plays a significant and multifaceted role in the endocrine system, influencing hormone secretion, endocrine axis function, and systemic homeostasis. It is produced in various endocrine tissues and acts as a key regulator in the hypothalamic–pituitary–gonadal and hypothalamic–pituitary–adrenal axes, mediating neuroendocrine function and influencing the secretion of hormones such as oxytocin, vasopressin, and luteinizing hormone-releasing hormone (LHRH).
- Glutamine (symbol Gln or Q) is an α-amino acid that is used in the biosynthesis of proteins. Glutamine plays a significant role in the endocrine system, particularly in the regulation of hormone secretion and metabolism within pancreatic islets and intestinal enteroendocrine cells.
- Glutathione plays a critical role in maintaining the health and function of the endocrine system, primarily through its actions as the body's master antioxidant and a key facilitator of detoxification processes. The endocrine system, which regulates hormones that control metabolism, growth, reproduction, and mood, is highly susceptible to damage from oxidative stress and environmental toxins. Glutathione helps protect endocrine cells, which are among the most metabolically active and thus vulnerable to oxidative damage, by neutralizing free radicals and preventing cellular dysfunction and premature cell death."
Individuals need to champion their own healthcare, know their systems, and push to be tested for any of the underlying conditions, working with healers to:
- focus on spiritual health regardless of any issue;
- do major detox of heavy metals, for example chlorella, milk thistle, celery, etc.;
- support the immune system with natural antimicrobials, zinc+copper+ionophore, or anthelmintics;
- rebalance micronutrients with healthy foods, and supplements;
- make sure of proper balance of nitirc oxide, glutamine and glutathione.
by Rose Rohloff
The following quotes are from combined multiple AI, open sources unless denoted, and not the opinion of the author.
Basics of Methylene Blue (MB) and Copper (Cu)
METHYLENE BLUE is a synthetic compound,produced through a chemical process involving the oxidation of N,N-dimethyl-phenylenediamine in the presence of sodium thiosulfate." COPPER is a natural, essential micronutrient for human health, playing vital roles in energy production, iron metabolism, forming red blood cells, maintaining connective tissues like bones and blood vessels, and supporting a healthy immune system. It also aids in nerve function by helping to produce neurotransmitters and is crucial for collagen and elastin production, which are vital for the strength and flexibility of tissues. " AI multiple sources | "MB is used to treat methemoglobinemia by chemically reducing ferric iron in hemoglobin to ferrous iron." "MB is a synthetic chemical compound, the first fully synthetic drug ever discovered, originally developed as an aniline dye for the textile industry in 1876 by Heinrich Caro." "Copper ions are vital for mitochondrial function, particularly for the cytochrome c oxidase (Complex IV) enzyme in the electron transport chain and superoxide dismutase 1 (SOD1), which are essential for energy production and antioxidant defense. Mitochondria rely on a tightly regulated transport and chaperone system to import and deliver Cu to these enzymes. Copper levels can influence mitochondrial dynamics, such as fusion & fission events, and affect mitophagy (the removal of damaged mitochondria). Cu imbalances, especially toxic copper can lead to severe mitochondrial damage, oxidative stress, or a unique form of cell death called cuproptosis, while Cu deficiency impairs energy production." |
Methylene Blue Inhibits In Vitro the SARS-CoV-2 Spike – ACE2 Protein-Protein Interaction – A Mechanism That Can Contribute to Its Antiviral Activity Against COVID-19 August 2020 DOI:10.1101/2020.08.29.273441 Link to Read
MB inhibitory activity against the interaction between SARS-CoV-2 spike protein and its cognate receptor ACE2, which is the first critical step initiating the viral attachment ... PPI inhibitory activity of methylene blue could contribute to its antiviral activity against SARS-CoV-2 even in the absence of light by blocking its attachment to ACE2-expressing cells.
MB inhibitory activity against the interaction between SARS-CoV-2 spike protein and its cognate receptor ACE2, which is the first critical step initiating the viral attachment ... PPI inhibitory activity of methylene blue could contribute to its antiviral activity against SARS-CoV-2 even in the absence of light by blocking its attachment to ACE2-expressing cells.
Also, review our blog The Tale of SARS-CoV (Covid) ACE2 Design 3/1/2024,
to understand the damage from the spike protein
to understand the damage from the spike protein
Methylene blue, an inhibitor of nitric oxide synthase & guanylate cyclase. Link to read
- Nitric oxide synthases (NOSs) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine. NO is an important cellular signaling molecule: modulate vascular constriction, insulin secretion, airway tone, ovary function, peristalsis, neuro and cardiac function/communication, etc.
- Guanylate cyclase 'is an enzyme ... exists in both a membrane-bound and soluble form in the cell. The membrane-bound form is a plasma membrane receptor, while soluble forms of guanylyl cyclase undergo activation by nitric oxide. Nitric oxide then functions as a primary messenger, amplifying the signal intracellularly. A vital second messenger, internalizing signals from various intercellular messengers like peptide hormones (e.g., atrial natriuretic peptide, B-type natriuretic peptide) and nitric oxide (NO), a gaseous neurotransmitter. This signaling pathway is essential for regulating' (essential body functions.)
MB and Cu - know interactions of micronutrients
"MB acts as a protective agent against copper-induced toxicity, particularly with copper oxide nanoparticles (CuO-NPs), and can be used to detect copper ions in water. Copper can participate in copper-catalyzed oxidation reactions to degrade methylene blue."
Also, review our blog Zinc (Zn) & Copper (Cu) - the importance inside the body 3/1/2024,
to understand the interplay of Zinc, Copper and Iron.
to understand the interplay of Zinc, Copper and Iron.
No studies of MB and Zinc (Zn) interactions in the body "no direct interactions between methylene blue and zinc are documented, research has explored a chemical interaction between methylene blue and zinc in a laboratory setting. A study described a new compound, "New Methylene Blue N zinc chloride double salt," which functions as a photosensitizer for photodynamic inactivation of fungi and is used in the determination of reticulocytes by binding to RNA. Furthermore, a 1970 study proposed a possible ion-associated complex, (MB)₂[Zn(SCN)₄]·2H₂O, formed during a spectrophotometric analysis of zinc using methylene blue and thiocyanate, indicating a specific chemical interaction under controlled conditions. These findings pertain to laboratory research and do not necessarily reflect interactions within the human body."
Pesticides, soil & metals - micronutrient impacts
"Bayer owns the rights to glyphosate, the active ingredient in the herbicide "Roundup", after acquiring Monsanto in 2018, (the original producer of Roundup)."
"Section 453 was attached to the FY26 Interior-Environment Appropriations Bill in the House. This would grant chemical companies immunity from 'failure to warn' lawsuits, such as those concerning glyphosate, the active ingredient in Roundup." Read the analysis following ...
"Section 453 was attached to the FY26 Interior-Environment Appropriations Bill in the House. This would grant chemical companies immunity from 'failure to warn' lawsuits, such as those concerning glyphosate, the active ingredient in Roundup." Read the analysis following ...
"Pesticides can increase copper toxicity indirectly, not by chemically enhancing copper but by altering environmental conditions that make copper more bioavailable. For example, some pesticides can create acidic environments that increase the release of copper ions from compounds, leading to greater copper toxicity in plants and soil organisms. Conversely, other pesticides, like glyphosate, can chelate (bind to) copper, reducing its bioavailability and thus its toxicity."
- Chelation: Glyphosate acts as a strong chelating agent, forming stable complexes with copper ions in both soil and water.
- Mobility:
This chelation can increase the mobility of copper in soil, potentially moving it into water systems where it can pose environmental risks. - Degradation:
The binding of glyphosate to soil components, including copper, can contribute to its inactivation in the soil.
- Reduced Toxicity: In soil, glyphosate can reduce the toxicity of copper to soil invertebrates, such as earthworms, by binding to the copper and decreasing its bioavailability.
- Increased Toxicity: In contrast, the glyphosate-copper complex itself can be more toxic to aquatic organisms, such as the water flea Daphnia magna, than glyphosate or copper alone.
- Oxidative Stress: Both individual and combined exposures to glyphosate and copper can induce oxidative stress
Heavy Metals and Pesticides Toxicity in Agricultural Soil and Plants: Ecological Risks and Human Health Implications, 2021
Heavy metals and pesticides are top of the list of environmental toxicants endangering nature. This review focuses on the toxic effect of heavy metals (cadmium (Cd), lead (Pb), copper (Cu), zinc (Zn)) and pesticides (insecticides, herbicides, and fungicides) adversely influencing the agricultural ecosystem (plant and soil) and human health. Heavy metals accumulation and pesticide residues in soils and plants have been discussed in detail. In addition, the characteristics of contaminated soil & plant physiological parameters reviewed ... Link to read
One source to review
Conclusion
People need to do self-research & first determine what is going
on within their bodies along with all the chemical reactions
of anything they are taking - across the board.
Learn Methylene Blue (MB), Nitric Oxide (NO) Copper (Cu), Zinc (Zn):
when to take and when not to take; together, separate, or apart.
on within their bodies along with all the chemical reactions
of anything they are taking - across the board.
Learn Methylene Blue (MB), Nitric Oxide (NO) Copper (Cu), Zinc (Zn):
when to take and when not to take; together, separate, or apart.
Individuals have different conditions and chemical balances:
- MB has a complex relationship with Cu;
- MB inhibits nitric oxide synthase and guanylate cyclase;
- L-arginine shown in double blind study to reduce hospitalizations of Covid patients by the Albert Einstein Institute in Italy, as well as a PA in Colorado, giving to patients in ER;
- MB listed as effective to combat specific disease processes (?short term use);
- No studies of MB reaction with Zn in the body that I can find.
Yungkingmito @yungkingmito X postings
https://x.com/yungkingmito/status/1980238478634860779
With repeated or high-dose use, methylene blue doesn’t stop at the brain. It seeps into the retinal pigment epithelium, the eye’s power grid where light, oxygen, and melanin never rest. Here, oxygen tension peaks and photons hit endlessly. The dye’s absorption peak mirrors sunlight itself (660nm). Under that frequency, the molecule flips into its triplet state, handing energy to oxygen and birthing singlet oxygen within micrometres of the membrane that keeps vision alive. That’s where the burn begins. Lipids ignite, photoreceptor disks are shed, stem-cell renewal halts. At first, a faint shadow drifts across the gaze but then hours later, the macula blanches, and the fovea falls silent. No pain, no redness, just a hole in the world that never heals. Even surface contact isn’t innocent. Methylene blue binds protein, holds light, and waits. Under oxygen and illumination, it reacts. A weakened barrier or careless dose lets it slip deeper, into a layer where transparency is sacred and recovery impossible. It doesn’t need blood to burn, only light, access, and time. And in the modern world, that fuse never sleeps. Daylight/full spectrum LEDs, red light panels, surgical lamps, even a camera flash all bleed the same 660 nm band that excites the dye. Once it’s in you, every photon becomes a spark. There was never clarity, only acceleration toward decay. Methylene Blue doesn’t heal light; it weaponizes it. Every photon that enters the eye becomes a blade against its own sight.
https://x.com/yungkingmito/status/1978616173710450955
Originally designed as a dye and emergency antidote, methylene blue manipulates the electron flow that powers your cells, but the same chemistry that can restore life in a hospital can quietly turn your bloodstream against you.
The social media crowd is oblivious to this, as they believe it just ‘boosts mitochondria” but in reality it squeezes your arteries and thickens your blood. By blocking the nitric-oxide → guanylate-cyclase pathway that keeps vessels relaxed, MB strips away your body’s natural pressure release. Arteries constrict, capillary flow slows, and every slowdown increases the odds of platelet collision and clot formation. Meanwhile its redox cycling oxidises fat and scars the vessel wall. Smooth endothelium becomes like sandpaper and platelets stick, fibrin nets begin to form and micro-clots bloom where you’ll never feel them forming.
The retina, kidneys and brain go first, the smallest pipes always clog before the mains. Don’t ever forget that and when you stack on intense training, fasting or cold exposure, the danger just compounds. Anything that shifts fluids like electrolytes, or even vascular tone can magnify MB’s constrictive effect. In trauma bays, under monitors, and certain circumstances MB really does saves lives, but used casually as a “mitochondrial hack,” can quite literally turn your circulation into a pressure chamber.
Not sure who on earth would believe it’s an enhancement, just remember whoever you see dosing it casually is inflicting self-induced vascular clots.
https://x.com/yungkingmito/status/1980238478634860779
With repeated or high-dose use, methylene blue doesn’t stop at the brain. It seeps into the retinal pigment epithelium, the eye’s power grid where light, oxygen, and melanin never rest. Here, oxygen tension peaks and photons hit endlessly. The dye’s absorption peak mirrors sunlight itself (660nm). Under that frequency, the molecule flips into its triplet state, handing energy to oxygen and birthing singlet oxygen within micrometres of the membrane that keeps vision alive. That’s where the burn begins. Lipids ignite, photoreceptor disks are shed, stem-cell renewal halts. At first, a faint shadow drifts across the gaze but then hours later, the macula blanches, and the fovea falls silent. No pain, no redness, just a hole in the world that never heals. Even surface contact isn’t innocent. Methylene blue binds protein, holds light, and waits. Under oxygen and illumination, it reacts. A weakened barrier or careless dose lets it slip deeper, into a layer where transparency is sacred and recovery impossible. It doesn’t need blood to burn, only light, access, and time. And in the modern world, that fuse never sleeps. Daylight/full spectrum LEDs, red light panels, surgical lamps, even a camera flash all bleed the same 660 nm band that excites the dye. Once it’s in you, every photon becomes a spark. There was never clarity, only acceleration toward decay. Methylene Blue doesn’t heal light; it weaponizes it. Every photon that enters the eye becomes a blade against its own sight.
https://x.com/yungkingmito/status/1978616173710450955
Originally designed as a dye and emergency antidote, methylene blue manipulates the electron flow that powers your cells, but the same chemistry that can restore life in a hospital can quietly turn your bloodstream against you.
The social media crowd is oblivious to this, as they believe it just ‘boosts mitochondria” but in reality it squeezes your arteries and thickens your blood. By blocking the nitric-oxide → guanylate-cyclase pathway that keeps vessels relaxed, MB strips away your body’s natural pressure release. Arteries constrict, capillary flow slows, and every slowdown increases the odds of platelet collision and clot formation. Meanwhile its redox cycling oxidises fat and scars the vessel wall. Smooth endothelium becomes like sandpaper and platelets stick, fibrin nets begin to form and micro-clots bloom where you’ll never feel them forming.
The retina, kidneys and brain go first, the smallest pipes always clog before the mains. Don’t ever forget that and when you stack on intense training, fasting or cold exposure, the danger just compounds. Anything that shifts fluids like electrolytes, or even vascular tone can magnify MB’s constrictive effect. In trauma bays, under monitors, and certain circumstances MB really does saves lives, but used casually as a “mitochondrial hack,” can quite literally turn your circulation into a pressure chamber.
Not sure who on earth would believe it’s an enhancement, just remember whoever you see dosing it casually is inflicting self-induced vascular clots.
by Rose Rohloff
There is gross lack of independent safety studies with specific science performed showing 5G + .... 10G for all immediate, short-term, intermediate, and long-term effects
ELECTROMAGNETIC RADIATION & FULMINATION (EMF)
| Risk of 5G rolled out, without safety studies, by Federal, State and Local governance. Communities were not asked regarding rollout, or informed regarding safety issues of 5G. Are we experiencing history repeating the dangers of severe medical handicapping and deaths of DDT, Asbestos, many FDA "approved" drugs recalled because they lacked safety, toxic fluoride in water, etc.? | ‘Those who do not learn history are doomed to repeat it.’ The quote is most likely due to writer and philosopher George Santayana, and in its original form it read, “Those who cannot remember the past are condemned to repeat it.” |
 |  |
Video overview, at 48 min (CBS reporting) to 56 min: 2018 Senate testimony FCC re: 5G wireless, U.S. Senator Richard Blumenthal (D-CT). FCC, "We rely on FDA ... No industry backed studies being done ... no safety studies." Sen Blumenthal, "No research ... we're flying blind here."
2G to 4G ... and now 5G +
Experts raising safety and health issues
Dr. Martin Pall full presentation to National Institute of Health link on Youtube
LTC (ret) Doc Pete Chambers MD, Green Beret, Special Operations, flight surgeon bioweapons expert (WMD, CBRNE, Biowarfare)
| Operation Crimson Mist - Rwanda 1994 .PDF “electromagnetically augmenting” anger into uncontrollable rage - electromagnetic pulsing | 5G friend or Foe .PDF Overview of the technology, use case examples of cease & desist because of health issues |
"Pulsed EMFs are in most cases much more biologically active than are non-pulsed, continuous wave EMFs (13 reviews). Because all wireless communication devices communicate via pulsations, they are potentially, and I believe actually, much more dangerous." Dr. Marin Pall
"Dr. Elizabeth Rauscher-Bise, who was a nuclear scientist and researcher at Lawrence Berkeley National Laboratory, and at Stanford Research Institute, Professor of Physics at John F. Kennedy University of California, research consultant to NASA and the U.S. Navy, and a member of IEEE, APS, AAAS, MAA, ANA, AAMI. Elizabeth Rauscher-Bise identified specific frequency effects to induce nausea, happiness and many other behavioral states decades ago. Clearly, Dr. Rauscher-Bise is an enthusiast: 'Give me the money and three months', she boasts, 'and I'll be able to affect the behavior of 80 per cent of the people in this town without their knowing it. Make them happy - or at least they'll think they're happy. Or aggressive.' (from Operation Crimson Mist .pdf above) https://elizabethrauscher.org/ biography
5G Roll-out Facing $1 Trillion Class Action Lawsuit - “THE 5G ROLL-OUT HAS NOT EVEN BEEN APPROVED BY THE AMERICAN PEOPLE; NOR HAS IT BEEN PROPERLY EVALUATED BY GOVERNMENT OR STUDIED BY QUALIFIED SCIENTISTS WITHIN THE IT, WIFI AND TELECOMMUNICATIONS INDUSTRIES.”(Source: 5G ROLL-OUT: An Ongoing National Emergency that Requires an Immediate Shutdown by the American People) Of course, the biggest concern about what is essentially a military deployment of 5G is that it represents “The Greatest Public Health Disaster in US History”.
Insurance Policies
Are healthcare insurance policies exempting care from rollout of electromagnetic radiation without the public's informed consent?
Title VII Legal Rights against mandates Navigating Title VII Civil Rights
Knowing your own Rights especially regarding illegal vaccine, shots, and mask mandates along with DEI.
The Government cannot mandate invasion internally of ones belief supporting protection of invasion of their body.
Title VII of the Civil Rights Act of 1964
Existing law in addition to the 1974 National Research Act.
Knowing your own Rights especially regarding illegal vaccine, shots, and mask mandates along with DEI.
The Government cannot mandate invasion internally of ones belief supporting protection of invasion of their body.
Title VII of the Civil Rights Act of 1964
Existing law in addition to the 1974 National Research Act.
Compiled Rose Rohloff from input by Dr. Peter McCullough and Dr. James Thorp
Many persons may have been illegally coerced into taking the Covid shots.(see blog entry regarding the 1974 National Research Act) The following is an extensive Spike Protein (SP-C) lab panel, sectioned into subpanels (a panel is a collection of several lab tests), for evaluating if you systems may have been impacted by the spike proteins - with or without existing symptoms. Note some individual labs may be duplicated in various panels and will not have to be duplicated. Champion your own care and consult with your choice of physician with informed consent.
General Tests and Evaluation of Cardiac
- Spike Ab* see endnote1 (by Lab Corp, Test Code 160236) + test #2
- Nucleocapsid and Spike qualitative Ab* see endnote1 - evaluates individuals with a history of COVID-19 ‘vaccination’, to aide in the diagnosis of Multi-system Inflammatory Syndrome in children (MIS-C) or adults (MIS-A).
- D-dimer = evaluation of incorrect/abnormal blood clotting in the body.
- hs-CRP = protein in the liver.
- hs-Troponin = is a protein that's found in the cells of your heart muscle. Normally, troponin levels in blood are so low that only the most sensitive types of tests can measure them. If your heart muscle is damaged, troponin leaks into your bloodstream with rising blood levels.
- BNP = brain natriuretic peptide test measures protein made by your heart and blood vessels, if higher reflects heart damage.
- ST-2 = protein, member of the interleukin (IL), is an indication of heart failure.
The following evaluate antibody (Ab) in your blood, proteins
made by the immune system to fight foreign bodies (bacteria, virus …)]**
made by the immune system to fight foreign bodies (bacteria, virus …)]**
- ANA** = looks for antinuclear antibodies in your blood.
- ANCA**= looks for antineutrophil cytoplasmic antibodies in your blood.
- RF** = looks for rheumatoid factor antibodies in your blood.
- anti-CCP** = looks for cyclic citrullinated peptide antibodies in the blood.
- anti-TPO**= Thyroid peroxidase is a type of protein (called enzyme) to make thyroid hormone. If the enzymes leak into the blood (when thyroid cells are damaged) the immune system makes antibodies against them. This test measures for these Ab in the blood.
- TSH = Thyroid stimulating hormone to evaluate the health of the thyroid gland. ***
- CMP = another panel to measure Comprehensive metabolic chemicals in your blood.
- CBC = another panel to measure Complete Blood Count evaluates Hemoglobin & Hematocrit (blood oxygenation), Red and the various White Blood cells.
- Vitamin D = essential for calcium absorption, nervous, muscle health and immune system.
- Galectin-3 = β-galactoside-binding lectin, expressed in the heart, the kidney, blood vessels, and macrophages and plays a role in tissue fibrosis, immunity, and the inflammatory response.
For women of reproduction age
- bundled Amenorrhea Profile = another panel to measure loss of monthly periods/amenorrhea, measuring various hormones, including TSH which does not need to be duplicated. ***
- Progesterone = hormone from the ovaries, prepares the uterus for pregnancy.
- AMH = Anti-mullerian Hormone, AMH is hormone made in male testes for making sperm. Ovaries in females make AMH.
For autoimmune and/or bleeding issues
- Clotting Profile = another panel to measure how your body is clotting.
- LA = Lupus Anticoagulant is another panel measuring auto-antibodies produced by the immune system that attack the body’s own phospholipids and proteins in cell membranes. LA occurs in other conditions besides Lupus.
1No commercially available test for circulating spike amounts are available at this time and will update as one becomes available. Serum Spike Antibody (Ab) is the surrogate at this time. Higher spike Ab titer correlates with severity of infection/long COVID. Pathologists are able to determine if tissue spike is from Shots/Injections versus infection via correctly performed autopsy, as per Dr. Ryan Cole in deposition of case.
“Normal” Value-ranges & Description of various tests
Some parameters vary slightly based on which lab is used - low or high readings should be determined by the specific lab being used at the time of lab test, and for individuals regarding their baselines, underlying conditions.
D-dimer CBC CRP CMP
Various Antibody testing to determine if your immune system is or is not fighting off a foreign substance.
Various Antibody testing to determine if your immune system is or is not fighting off a foreign substance.
TSH: ***
Amenorrhoea Panel
- T4 thyroid hormone test
- T3 thyroid hormone test
- Thyroid antibodies test to help diagnose an autoimmune thyroid disorder.
Amenorrhoea Panel
- LH hormone secreted by pituitary gland located in your brain, ovaries and ovulation.
- FSH hormone secreted by pituitary gland located in your brain, ovulation and menstruation.
- Prolactin hormone secreted by pituitary gland located in your brain, breasts and milk production.
- TSH ***
- PT (-INR) prothrombin is protein your liver produces, correct stopping of bleeding/clotting.*
- PTT partial thromboplastin time measures factors to see correct stopping of bleeding/clotting.
- Thrombin measures how well fibrinogen is working.
- Platelet Count cells in your blood to help with clotting.
- Bleeding Time analyzes how effective small blood vessels in your skin close up, clots.
- Factor V assay a special protein to help with clotting of the blood.
9th Circuit Court Ruling |  |
"Ninth Circuit Court Full Details... read each bullet point baby!
(1) The court ruled that the district court misapplied the 1905 Jacobson case because LAUSD relies on a drug that Plaintiffs plausibly alleged did not prevent the spread of the virus.
(2) LAUSD has changed its mind about requiring the vaccine and therefore, the case cannot be mooted because LAUSD has proven it will just enact it again later.
(3) The court said, "But even if the materials offered by LAUSD are subject to judicial notice, they do not support rejecting Plaintiffs’ allegations. LAUSD only provides a CDC publication that says “COVID-19 vaccines are safe and effective.” But safe and effective for what? LAUSD implies that it is for preventing transmission of COVID-19 but does not adduce judicially noticeable facts that prove this."
(4) "Pursuant to more recent Supreme Court authority, compulsory treatment for the health benefit of the person treated—as opposed to compulsory treatment for the health benefit of others— implicates the fundamental right to refuse medical treatment. Plaintiffs’ allegations here are sufficient to invoke that fundamental right. Defendants note that the vaccination mandate was imposed merely as a “condition of employment,” but that does not suffice to justify the district court’s application of rational-basis scrutiny."
(5) MUST READ THIS..."In Washington v. Glucksberg, 521 U.S. 702 (1997), the Court explained that Cruzan’s posited “‘right of a competent individual to refuse medical treatment’” was “entirely consistent with this Nation’s history and constitutional traditions,” in light of “the common-law rule that forced medication was a battery, and the long legal tradition protecting the decision to refuse unwanted medical treatment.” Id. at 724–25 (citation omitted). Given these statements in Glucksberg, the right described there satisfies the history-based standards that the Court applies for recognizing “fundamental rights that are not mentioned anywhere in the Constitution.” Dobbs v. Jackson Women’s Health Org., 597 U.S. 215, 237–38 (2022). The Supreme Court’s caselaw thus clarifies that compulsory treatment for the health benefit of the person treated—as opposed to compulsory treatment for the health benefit of others— implicates the fundamental right to refuse medical treatment." https://cdn.ca9.uscourts.gov/datastore/opinions/2024/06/07/22-55908.pdf…
(1) The court ruled that the district court misapplied the 1905 Jacobson case because LAUSD relies on a drug that Plaintiffs plausibly alleged did not prevent the spread of the virus.
(2) LAUSD has changed its mind about requiring the vaccine and therefore, the case cannot be mooted because LAUSD has proven it will just enact it again later.
(3) The court said, "But even if the materials offered by LAUSD are subject to judicial notice, they do not support rejecting Plaintiffs’ allegations. LAUSD only provides a CDC publication that says “COVID-19 vaccines are safe and effective.” But safe and effective for what? LAUSD implies that it is for preventing transmission of COVID-19 but does not adduce judicially noticeable facts that prove this."
(4) "Pursuant to more recent Supreme Court authority, compulsory treatment for the health benefit of the person treated—as opposed to compulsory treatment for the health benefit of others— implicates the fundamental right to refuse medical treatment. Plaintiffs’ allegations here are sufficient to invoke that fundamental right. Defendants note that the vaccination mandate was imposed merely as a “condition of employment,” but that does not suffice to justify the district court’s application of rational-basis scrutiny."
(5) MUST READ THIS..."In Washington v. Glucksberg, 521 U.S. 702 (1997), the Court explained that Cruzan’s posited “‘right of a competent individual to refuse medical treatment’” was “entirely consistent with this Nation’s history and constitutional traditions,” in light of “the common-law rule that forced medication was a battery, and the long legal tradition protecting the decision to refuse unwanted medical treatment.” Id. at 724–25 (citation omitted). Given these statements in Glucksberg, the right described there satisfies the history-based standards that the Court applies for recognizing “fundamental rights that are not mentioned anywhere in the Constitution.” Dobbs v. Jackson Women’s Health Org., 597 U.S. 215, 237–38 (2022). The Supreme Court’s caselaw thus clarifies that compulsory treatment for the health benefit of the person treated—as opposed to compulsory treatment for the health benefit of others— implicates the fundamental right to refuse medical treatment." https://cdn.ca9.uscourts.gov/datastore/opinions/2024/06/07/22-55908.pdf…
by Rose Rohloff
THE ORIGINAL HIPPOCRATIC OATH ALTERED & EXPANDED
Caring for health will not improve until we bring back oaths: binding testimonials for committed healers. The privilege and honor of being in charge of lives with integrated souls is not a job; it is a calling. We, individual Christians - not schools, governmental agencies or regulatory bodies - hold each other to the highest standards. And, oaths are taken and upheld by individuals. The following expansion on the original Hippocratic oath is for MD/DO/DC, PA, RN/LPN, Naturopath, Therapists, etc. anyone within the industry of healing.
I (name) will perform my duties with faith and trust in God as my guide, and continually learn as long as I perform my duties. I will impart a knowledge of the art of healing, mentoring and teaching those I serve. Above all else, I will abstain from whatever is deleterious, mischievous, malfeasance or unjust to those being treated, and I will not break what is not broken, for that is doing harm.
I will use those dietary regimens which will benefit the persons I see, according to my greatest ability and judgment, always providing proper informed consent of all alternatives, ramifications, risks and possible outcomes - for any and all treatments, herbs, supplements, medicines, procedures and surgeries.
I will preserve the unalienable rights endowed by the Creator on every individual human life, from conception to natural death. I will not give a lethal drug to anyone if I am asked, nor will I advise such a plan for intentionally ending a life; and similarly I will not give a woman or cause an abortion. In purity and according to divine law will I carry out my life and my art. I will enter them for the benefit of the sick, avoiding any voluntary act of impropriety or corruption, including the seduction of women or men. Whatever I see or hear in the lives of those I care for, whether in connection with my professional practice or not, I will keep secret, as considering all such things to be private.
I will, remain faithful to this oath and fiercely and honorably battle illnesses regardless of societal coercion, derision by others or imperilment to my livelihood and life. So long as I maintain this Oath faithfully and without corruption, may it be granted to me to partake of life fully, and the practice of my art to heal and mentor for staying healthy, giving glory to God for His gift of healing. However, should I transgress this Oath and violate it, may the opposite be my fate.
So help me GOD.
Clinicians post degrees; what about posting the oath
they abide by, adhere to, and practice within its ethos?
they abide by, adhere to, and practice within its ethos?
by Rose Rohloff
Each individual should be in charge of their own healthcare decisions, safety surroundings, and be treated individually. So, a good question to ask, "Who actually is in charge?"
Laws and Executive Orders (EOs) regarding healthcare under "public health"
Created by Todd Callender, Esquire
H.R.3832 - Disease X Act of 2023 118th Congress (2023-2024)
Open "disease" cart blanc for them to choose (or orchestrate?)
Open "disease" cart blanc for them to choose (or orchestrate?)
‘World Health Organization (WHO) Has No Authority to Dictate U.S. Health Policy’ factcheck.org
March 2, 2023 "Although the accord is being called ... a treaty or another kind of binding agreement, such as the WHO Framework Convention on Tobacco Control, or a nonbinding agreement, such as the Paris Climate Accord. “As with all international instruments, any accord, if and when agreed, would be determined by governments themselves, who would take any action while considering their own national laws and regulations,” a WHO spokesperson told us." Federal and Local Governments would be in charge regarding any Rights violations. The accord is accumulation of monies $$$ to be "distributed" to various countries/persons, in the name of public health.
March 2, 2023 "Although the accord is being called ... a treaty or another kind of binding agreement, such as the WHO Framework Convention on Tobacco Control, or a nonbinding agreement, such as the Paris Climate Accord. “As with all international instruments, any accord, if and when agreed, would be determined by governments themselves, who would take any action while considering their own national laws and regulations,” a WHO spokesperson told us." Federal and Local Governments would be in charge regarding any Rights violations. The accord is accumulation of monies $$$ to be "distributed" to various countries/persons, in the name of public health.
| James Roguski - researcher, author, natural health proponent and an activist. In March 2022, James uncovered documents regarding proposed amendments to the International Health Regulations (IHRs), and was instrumental in raising awareness about them. James now works to expose the WHO's hidden agenda with ongoing attempts to amend the IHRs. | Let’s get out of the WHO  Click to listen to full presentation author questions at 1:45:46 |
Are individual healthcare insurance policies, the underwriters
of policies, being invalidated without the knowledge of people,
and against their choice - through lack of knowledge,
lack of informed consent, and through illegal coercion?
of policies, being invalidated without the knowledge of people,
and against their choice - through lack of knowledge,
lack of informed consent, and through illegal coercion?
Endocrine Disrupting Chemicals (EDCs)
Major underwriter for insurance, exemption for Endocrine disrupting chemicals (EDCs)
Pfizer document - animal testing, spike protein to all organs including endocrine system
by Rose Rohloff
Overview of the bio weapon creation released and injected with the shots, active ingredient spike proteins and viral vectors.
- EcoHealth Alliance (EHA) proposed to DARPA with intentional design
- DARPA refused because gain-of-function (GOF)
- EHA did anyways under the Health & Human Services (HHS-NIAID)
- The shots contain ACE2 binders - spike proteins
- Fauci at NIAID knew it was GOF
Exhibit A: EcoHealth Alliance proposal to DARPA page 3; intention = GOF as per DARPA
Exhibit B: Pfizer document components of the shots
Exhibit C: ScienceDirect "ACE2, TMPRSS2 distribution and extrapulmonary organ injury in patients with COVID-19" Nov 2020
Exhibit D: Un of NC letter GOF
* Date: written 2015 posted 2016
* Not natural: chimeric infectious clones, GOF
* Not natural: chimeric infectious clones, GOF
Exhibit E: Baric, Univ NC, Chapel Hill - 2016
| AARON SIRI GIVES TESTIMONY - ARIZONA STATE SENATE |  |
Listen with this link https://thehighwire.com/ark-videos/aaron-siri-gives-testimony-on-the-floor-of-arizona-state-senate/
FDA working in support of pharma - no clinical trial testing of vaccines with "circular approval."
by Rose Rohloff
An India folklore, regarding lack of awareness, demonstrates the current myopic view of various specialists, who look at isolated symptoms without comprehensive assessments, resulting in poor or lack of diagnosing of real issues to address in patients. The industry push to eliminate primary care, teaching people they don’t need a primary doctor, or using primary care doctors as simple pass-through without diagnosing, handing off to multiple other doctors, has resulted in the loss of care coordination, overdosing multiple medications with contraindications/side effects, with increased conditions because multiple doctors only look at their individual view.
An India folklore, regarding lack of awareness, demonstrates the current myopic view of various specialists, who look at isolated symptoms without comprehensive assessments, resulting in poor or lack of diagnosing of real issues to address in patients. The industry push to eliminate primary care, teaching people they don’t need a primary doctor, or using primary care doctors as simple pass-through without diagnosing, handing off to multiple other doctors, has resulted in the loss of care coordination, overdosing multiple medications with contraindications/side effects, with increased conditions because multiple doctors only look at their individual view.
The following version of the blind men and the elephant story is from Peacecorp.gov, and is analogous to the existing healthcare system of specialists.
Long ago, old blind men were curious about the many stories they heard about elephants. The men were led to one for each person to independently touch the animal.
Long ago, old blind men were curious about the many stories they heard about elephants. The men were led to one for each person to independently touch the animal.
- The first blind man reached out and touched its side. "An elephant is smooth and solid like a wall!" he declared. "It must be very powerful."
- The second blind man put his hand on the elephant's limber trunk. "An elephant is like a giant snake," he announced.
- The third blind man felt the elephant's pointed tusk. "I was right," he decided. "This creature is as sharp and deadly as a spear."
- The fourth blind man touched the elephant's leg. "What we have here," he said, "is an extremely large cow."
- The fifth blind man felt one of its giant ears. "I believe an elephant is like a huge fan or maybe a magic carpet that can fly over mountains and treetops," he said.
- The sixth blind man gave a tug on the elephant's coarse tail. "Why, this is nothing more than a piece of old rope." he scoffed.
| The six blind men determined what they knew on limited assessment of only touching one part of the elephant, just as individual doctors only look at single symptoms; for example, cardiologist only looks at the heart, nephrologist only looks at kidney, endocrinologist only looks at the endocrine system ... |  |
All body systems impact each other, designed to function as a whole, for a well orchestrated, compensatory mechanism. By only looking at individual symptoms of isolated systems, patient’s underlying conditions are not addressed for health, and can often be fulminated and/or obscured by medications. And, the reason primary care doctors are imperative for knowing the whole patient, knowing how to diagnose and treat many conditions. Primary doctors should only pass their patients to specialists for complicated, complex conditions, while always following their patient and maintaining all coordination with any other doctors.
| by Rose Rohloff We need to change the dialogue, remove panic. This is a virus that can infrequently lead to death, as opposed to "a deadly virus." If this veteran can fight it off, so can millions of people focused on strengthening their immune systems. |  |
With perpetual reporting of the COVID-19 virus, there has been a lot of panic reaction from the public, fostered by the media, as well as from local clinical staff. These reactions have brought existing issues in the healthcare system to the forefront, that we can address go forward, especially for discernment to champion better quality of care. The following two use case examples happened last week, which demonstrate panic reactions from clinicians, the need for good primary care, and the need to address care standards, especially in crisis, with sense at the delivery level.
An immune suppressed mother has three children, one being a 10 yr. old daughter who woke with a 102 temperature and a sore throat. The mother is not reactionary, having good instinct regarding when her children are fighting off bugs, building up their immune systems. She phoned the pediatrician to ask for testing if it is strep or a virus. The pediatrician stated they only test for COVID-19 if someone is hospitalized, and they would not do a strep test, “Don’t bring your child in”, and then the pediatrician went on a rant about social distancing, “This virus will not end …” (with no reported cases in the area) etc. and simply ordered Amoxicillin.
 | The mother phoned me commenting, "I don't feel comfortable with this situation, the doctor's reaction and their approach. |
I don't want to give my daughter an antibiotic if she doesn't need it, and especially if it is a virus, let alone the Corona virus." Removing all emotion from the situation with her, we discussed getting zinc in EZC Pak from the CVS a mile away, that she could pick up via their drive through, along with foods high in Vitamin A to boost her daughter's immune system. I also called the local Urgent Care center explaining the situation: a mother immunosuppressed, her daughter is in the EMR system, she just wants a strep swab to avoid unnecessary antibiotics, to please have a nurse do the swab through the car window when she drives up - avoiding any cross contamination issues. They stated no problem.
| The mother called the Urgent Care center and they informed her she got bad information, they would absolutely not do a swab from the car, she must come in. She stated, “You want me to walk into that center with sick people along with my two other smaller, healthy children so in less than a minute you can swab my other daughter’s throat to verify if she needs an antibiotic?” They told the mother that she could not bring that many people into the facility with her. The mother asked, “What exactly to do you expect me to do then to protect myself, and what do you want me to do with my other kids?” The healthcare personnel demonstrated panic, without some basic sense. I finally asked the mother what she wanted to do. She stated, “My daughter is alert, drinking, not that bad. I am going to get Zinc and good foods, push fluids especially with warm lemon and honey, have her gargle with warm salt water, and see how she is in 24 hours.” The daughter’s temperature was 99 by nightfall, and 98 degrees by the next day without a sore throat. If the mother had not questioned the panic of the doctor and nurse, her daughter would have been put on an unnecessary antibiotic, opening her up to secondary infections, and exposing herself to unnecessary virus and bacteria while being immunosuppressed. | From the NIH Amoxicillian: Additionally, there is a moderately increased risk of secondary Clostridium difficile (C-diff) colitis when compared with other classes of antibiotics. Females taking this medication can also develop vaginitis secondary to vaginal mycosis or candidiasis. (Our bodies keep C-diff and candidiasis in check with our needed good bacteria.) The next day, the mother stated, "The doctor lost all credibility with me going on in a panic about the issues with the COVID-19, "this will never end by Easter, etc." when the hospitals have little volume, no reported cases. "She refused to do any history and basic assessment to swab my daughter to rule out strep before writing a prescription." Our healthcare system has been broken regarding the lack of some basic sense at the ground level, with reactionary versus proactive care; missing great primary care doctors, avoiding the quick symptom = writing a prescription form of care.  |
The same week, a second mother of four small children, one being a seven year old who was having sore joints and some blood in her urine. The doctors in Green Bay did a wonderful job of a full, very detailed history and then exam with targeted tests, quickly diagnosing Rheumatic Fever. Her and her other three, healthy children were instructed to do proactive strep testing since they all had close exposure with the daughter. "The center made us feel like lepers. Instead of simply coming out to the car to meet us, they brought us to an empty lobby with a nurse who came out in a full hazmat suit to do simple strep swabs. The nurse freaked out when my son simply cleared is throat, creating anxiety, complaining, "He just coughed."
The clinicians throughout both cases should have been calming, simply asking good questions, and then only ordering the correct test before ordering medication. And, in both cases, clinicians could have had the tests quickly, avoiding the waste of hazmat gear, not frightening healthy family members as well as not exposing them to potential germs in the health facilities - avoiding cross contamination issues.
What we need to focus heavily on:
- Great education nationally in diet to strengthen the immune system. Great nutrition understanding regarding what vitamins to focus on, removal of sugars from the diet, etc. The idea of waiting on vaccines after the fact, for every virus, is not realistic or proactive.
- Better testing of high risk patients regarding their health with focus on strengthening their own immune system.
- Zinc and other nutrients when one is immediately feeling poor. Fights inflammation, works with immune system or exposure to infectious persons.
 Replay video, with permission via Dave Chase, Health Rosetta https://vimeo.com/403748057/1b07436d73 | Health Rosetta hosted a wonderful webinar with Chief Medical Officers (CMOs) from around the country speaking, without panic, about the effective care of their patients at home with COVID-19. Their stories demonstrating the importance of shifting back to great primary care. |
One point stood out regarding their focus that is so often missing in health systems: seeing 'clean' patients first, and then seeing contagious patients grouped together, ensuring avoidance of cross contamination, and minimizing the volume of masks, gowns or hazmat suits used.
Hopefully, many good things will come from this virus experience to positively shake up our healthcare system, including basic sense procedures, with the importance to rebuild and focus on great primary care again. Another glaring issue to address is the role of clinicians as cool, calm professionals, removing emotion when instructing with full information, with clearly explained options for informed consent and decision-making for delivery of quality care.
Hopefully, many good things will come from this virus experience to positively shake up our healthcare system, including basic sense procedures, with the importance to rebuild and focus on great primary care again. Another glaring issue to address is the role of clinicians as cool, calm professionals, removing emotion when instructing with full information, with clearly explained options for informed consent and decision-making for delivery of quality care.
by Rose Rohloff
It is known taking medications will impact various lab values. For example, Diuretics e.g. Lasix (Furosemide), can cause low potassium levels. There is an interesting article in Medscape, Which Drugs Interact With Lab Tests? Jun 18, 2019., addressing the fact that certain medications can also interact with the actual processing of certain lab tests causing inaccurate results.
It is known taking medications will impact various lab values. For example, Diuretics e.g. Lasix (Furosemide), can cause low potassium levels. There is an interesting article in Medscape, Which Drugs Interact With Lab Tests? Jun 18, 2019., addressing the fact that certain medications can also interact with the actual processing of certain lab tests causing inaccurate results.
A recent view of the prescribing information for 1368 prescription drugs found that 134 (9.8%) included information about a specific lab test interaction, 31 (2.3%) stated that the drug did not interfere with lab tests, and four stated that there was no available information.[1] ... |  Patients, families and caregivers need to be aware of what name, class, internal action, as well as all other medication interactions for every medication, vitamin and supplements being taken. As Dr. Scott shares as insightful, it is also important before getting lab values done to understand if any medications being taken will impact labs to be processed and cause false results. |
by Linda Lybert
President/ Healthcare Surfaces Expert, Founder/Executive Director Healthcare Surfaces Institute
Privacy curtains must be addressed and as I talk with healthcare professionals about this issue I get mixed reactions. Digging deep into the issue the biggest problem is the amount of time and labor it takes to actually change the curtains out. "It is backbreaking and we don't have enough staff to actually do this on a regular basis." Every facility sets its own standards for changing privacy curtains and the responsibility lays with operations. Policies range from change when visibly soiled (NOTE: microbes can't be seen) to once a quarter and even once a year and any time in-between. As research continues to be published it is clear to mitigate the spread of infections solutions this must be part of a solutions bundle addressing all surfaces! See LinkedIn Post with full Study: Patient Privacy Curtains represent Infection Risk
Linda Lybert is an amazing expert in healthcare surfaces. The same circumstances existed 20 yrs ago, but clinicians were properly trained & executed safety processes/avoided cross contamination; learning in school movement memory e.g. wash hands after closing curtains before touching patients, use elbows to open curtains to enter or push all the way open, etc. #1 issue - lack of clinical training, laziness, and inadequate adherence of movement memory for proper safety protocols. Rose Rohloff
by Rose Rohloff
The 2009 HITECH Act and the Center for Medicare Medicaid Services’ (CMS) Meaningful Use regulations caused a massive spend for electronic medical records (EMRs), the push for interoperability, as the solution to healthcare quality. However, EMRs are not solutions - along with massive IT overhead spend with decreasing quality - because in a high percent of instances, nurses and doctors don’t even read them.
A 40-year old mother went to the doctor after treating herself holistically for some laryngitis, stuffy nose, congested sinus, with continued symptoms after five days. After an exam, the doctor stated, “I am not going to give you antibiotics. You do not have a fever; your lungs sound clear. It looks like a little virus with severe allergies. I recommend an antihistamine.” The patient told him, “Thank you for not putting me on antibiotics when they are not needed, that makes me happy.” He responded, “I am glad you are glad.”
A 40-year old mother went to the doctor after treating herself holistically for some laryngitis, stuffy nose, congested sinus, with continued symptoms after five days. After an exam, the doctor stated, “I am not going to give you antibiotics. You do not have a fever; your lungs sound clear. It looks like a little virus with severe allergies. I recommend an antihistamine.” The patient told him, “Thank you for not putting me on antibiotics when they are not needed, that makes me happy.” He responded, “I am glad you are glad.”
He then said something and the patient responded, “I have MS.” He responded, “Oh wait, you have Multiple Sclerosis?”
This story is sadly too often the new normal, numerous instances of patients and their caregivers stating issues of diagnosing with medication prescription, or misdiagnosis; the doctor or nurse having no idea of pre-existing conditions or a full list of medications currently being taken, a lack of care coordination or care planning because the time was not taken to simply read the chart (whether written or electronic), and ensuring a comprehensive history followed by the necessary physical assessment.
No physician or nurse should walk in to care for a patient without first having read the patient’s record, knowing all current information, the last visit/healthcare encounter, chronic conditions/comorbidities, and all medications; then, asking for updates of changes. Unfortunately, even without having to decipher poor handwriting, being able to read clean typed text, clinicians are not simply reading the basics of information they should before doing any diagnosing, planning and delivering of care - especially prescribing of medications.
This story is sadly too often the new normal, numerous instances of patients and their caregivers stating issues of diagnosing with medication prescription, or misdiagnosis; the doctor or nurse having no idea of pre-existing conditions or a full list of medications currently being taken, a lack of care coordination or care planning because the time was not taken to simply read the chart (whether written or electronic), and ensuring a comprehensive history followed by the necessary physical assessment.
No physician or nurse should walk in to care for a patient without first having read the patient’s record, knowing all current information, the last visit/healthcare encounter, chronic conditions/comorbidities, and all medications; then, asking for updates of changes. Unfortunately, even without having to decipher poor handwriting, being able to read clean typed text, clinicians are not simply reading the basics of information they should before doing any diagnosing, planning and delivering of care - especially prescribing of medications.
by Rose Rohloff
The baby boomer generation is now the growing population of elderly with more care needs in home health. As the current generation is being faced with the care responsibilities, many are still unaware concerning various facets of caring for others: advanced directives and living wills; stimulation and diets for mental sharpness, questions to ask and quality of care considerations with becoming power of attorneys - the core of healthcare awareness. One area is focused heavily within hospitals and other care delivery environments, but yet over looked in private homes – surface areas and cleanliness.
A popular trend in houses is the use of marble and granite as counter tops. A leading surface expert, Linda Lybert President of Healthcare Surface Consulting stated, “Granite and Marble are like large sponges you cannot wring out.” The photo displayed shows the build up of E. coli bacteria in the pores of stone. According to Ms. Lybert, even when sealed, the porousness is reduced, but not eliminated. And, bleach is not able to eliminate once they reside in the crevices.
A popular trend in houses is the use of marble and granite as counter tops. A leading surface expert, Linda Lybert President of Healthcare Surface Consulting stated, “Granite and Marble are like large sponges you cannot wring out.” The photo displayed shows the build up of E. coli bacteria in the pores of stone. According to Ms. Lybert, even when sealed, the porousness is reduced, but not eliminated. And, bleach is not able to eliminate once they reside in the crevices.
All surfaces in the home, counter tops, floors including laminates, tile and grout need diligent daily cleaning and disinfection. However, Ms. Lybert brings awareness that regarding "stone surfaces, including granite/marble, there is no effective means to disinfect these surfaces." Consider, "granite is an underground aquifer for our water filtering out all kinds of things. Given the right kind of environment, heat and moisture, bacteria will grow."
As the elderly begin to lose their mobility and agility, it is important to maintain clean surfaces in bathrooms and bedrooms, along with the most important surface being the skin. Diligent hand washing and bathing is important throughout the day to avoid cross contamination from the loved one you are caring for, as well as to them. The other surface area to be conscientious of is bedding. When excrement accidents occur, it is important to wash bedding with very hot water to not only clean them, but also kill the microbes.
Clostridium difficile (commonly known as C-diff) "is in the community and found in outpatient settings. There are significant risk factors in patients who are immunosuppressant, individuals who have been on antibiotic therapy, and the elderly population." C-diff is a secondary, very dangerous and potentially deadly infection after antibiotic use. [read article] It is important to those in the community to have appropriate antibiotic prescriptions and use, especially avoiding unnecessary broad spectrum antibiotic use which targets the "good" bacteria you need internally (and not on external surfaces) to kill off C-diff.
As the elderly begin to lose their mobility and agility, it is important to maintain clean surfaces in bathrooms and bedrooms, along with the most important surface being the skin. Diligent hand washing and bathing is important throughout the day to avoid cross contamination from the loved one you are caring for, as well as to them. The other surface area to be conscientious of is bedding. When excrement accidents occur, it is important to wash bedding with very hot water to not only clean them, but also kill the microbes.
Clostridium difficile (commonly known as C-diff) "is in the community and found in outpatient settings. There are significant risk factors in patients who are immunosuppressant, individuals who have been on antibiotic therapy, and the elderly population." C-diff is a secondary, very dangerous and potentially deadly infection after antibiotic use. [read article] It is important to those in the community to have appropriate antibiotic prescriptions and use, especially avoiding unnecessary broad spectrum antibiotic use which targets the "good" bacteria you need internally (and not on external surfaces) to kill off C-diff.
by Rose Rohloff
But, what is value? Is society conditioned to accept low quality as value, because a lower standard has become the norm?
| Value is a relative term based upon personal perception, and oftentimes great marketing. True value is based upon insightful knowledge of what entails quality along with the cost of delivering goods and services. Value-based care is the new buzz for basing reimbursement in the healthcare industry. But again, what is value care: personal perception, marketing, cost? |  |
This article was conceived after several conversations regarding what defines quality care, with veteran clinicians (nurses and doctors), insurance brokers, as well as numerous 40-80 year olds who make up the typical population across the country. Using the following encounter as an example, I want to review what determines true value of care delivery compared to the normal perception being marketed.
A surgeon office within a surgical center, (the surgeon with privileges at two leading health systems), has 5-star Healthgrades ratings, including comments: the staff is courteous; appointments start on time; the Physician Assistant (PA) is very intelligent, knowledgeable, articulate and caring; and the surgeon with a benchmark performance staff. There are also one star ratings including a comment the staff is not properly trained and do not know how to maintain a sterile environment.
The primary issue with such score deviations is determining if poor marks are isolated instances (one offs); or, if the variance of only highest and lowest reflect the knowledge of reviewers. Are the high ratings from non-healthcare persons based on perception of the veneer friendliness and scheduling, with one star comments based on specific quality requirements, care competency posted by those with healthcare insight/experience?
As a 35+ year healthcare veteran, an answer was determined accompanying a Medicare patient ‘John’, in his mid-80s who experiences early stage dementia, to the office for a post-op visit for a leg stint placement.
The primary issue with such score deviations is determining if poor marks are isolated instances (one offs); or, if the variance of only highest and lowest reflect the knowledge of reviewers. Are the high ratings from non-healthcare persons based on perception of the veneer friendliness and scheduling, with one star comments based on specific quality requirements, care competency posted by those with healthcare insight/experience?
As a 35+ year healthcare veteran, an answer was determined accompanying a Medicare patient ‘John’, in his mid-80s who experiences early stage dementia, to the office for a post-op visit for a leg stint placement.
| Upon arriving, another elderly patient (80s) was sitting outside, unattended in wheelchair, hot sun, 100 degree weather, no water. When asked why he was there, he stated, “I can’t stand the freezing air conditioning inside while waiting for a ride.” After walking John into the lobby, the gentlemen clearly seen through the glass door was pointed out to the receptionist stating that he was left in hot sun, no water, unattended. The receptionist stated, “It is his choice to stay out there.” I then stated, “Get someone to check on him, give him water, put him in the shade and check when his ride is supposed to arrive and monitor him if it is delayed or bring him inside.” One person escorted us back to exam room. She did not introduce herself or her title. She proceeded to take the blood pressure with no other vital signs (unknown if a secretary, an aide, a nurse or tech). She then asked the patient, “How much do you weigh?” He gave a number. As patient champion I responded, “He doesn’t know, he has not weighed himself. You need to weigh him yourself.” She responded, “We don’t have a scale.” She then left. I followed her witnessing her documenting the incorrect data. | I reiterated he has dementia with no idea how much he weighs. She replied, “It doesn’t matter anyways, we just need to put something in the record.” She was reflecting an 11 pound weight loss from previous recording. It is unclear if they performed the previous weighing, if it was done just prior to surgery to determine proper anesthesia delivery for his surgery.  Another woman in scrubs entered the exam room without introducing herself or her title, asking John to remove his shoes and socks. (The scheduled appointment was with the PA so the patient assumed her identity.) She asked him if his wound was healed and he replied, “Yes.” She documented something in the chart without ever assessing his wound for healing or determining if there was infection. She bent down and felt his feet with her whole hands stating they feel warm, and then asked if he had numbness in his feet. John responded, “Yes.” | Having worked as a registered nurse (RN) in cardiovascular and neuro intensive care units (ICUs), I know she never did pedal (foot) pulse checks x4 comparing both feet. She never assessed location of numbness, or if chronic/intermittent, positional with sitting/, standing, walking, etc. The family had asked if aspirin could be stopped as the patient has experienced nose bleeds in the past. The staff person responded yes and since there was 90% blockage of the previous stint, it was cleaned out and continue Plavix. There was no establishment of lab work as part of care plan determining effectiveness of the medications, especially since the previous stint occluded. "1,750 or so stent patients are also prescribed Plavix to prevent clots from forming around the stent, but of that group, approximately 500 (29%) carry a genetic variation that prevents them from converting Plavix into its active form. This gene-related lack of response stands to be "especially severe" in about 50 (3%) of those patients, who won't derive any benefit from Plavix - 2010 Vanderbilt Medical Center |
She then stated they would be ordering an ultrasound as a standard post-op test to determine the effectiveness of the stint - over three weeks after the procedure.
Why didn't they do the ultrasound during the post-op visit to have results to make sure the stint was effective? No doppler was used to assess extremity blood flow.
She stood up, touched the paperwork, the marker and laminate sheet then touched the door handle leaving – never having washed her hands before assessing the patient, nor after putting her hands on his feet.
Perceived value based on quality versus true value and cost
The office visit was charged to Medicare, with an elderly patient perceiving the staff as nice during the office visit.
The care competency and quality as true value-based care during the visit includes:
- lack of basic cleanliness standards with severe cross contamination practices
- no introduction of name or title of any staff member
- fraudulent documentation in the electronic medical record (EMR)
- no assessment performed during a specific post operative visit (a family member could have taken the BP and said his feet felt warm.)
- lack of care planning and evaluation of medication regime
- unnecessary secondary office visit charging for follow up
- another elderly patient left unattended in the hot sun
If the U.S. healthcare system wants to achieve true value-based care, we need an educated population, higher accountability of staff standards with the ability to send evaluations direct to payers based on specific facts and not emotion, and surveys must include care competency reviews versus only veneer questions of politeness, room appearances, and on time scheduling.
The care competency and quality as true value-based care during the visit includes:
- lack of basic cleanliness standards with severe cross contamination practices
- no introduction of name or title of any staff member
- fraudulent documentation in the electronic medical record (EMR)
- no assessment performed during a specific post operative visit (a family member could have taken the BP and said his feet felt warm.)
- lack of care planning and evaluation of medication regime
- unnecessary secondary office visit charging for follow up
- another elderly patient left unattended in the hot sun
If the U.S. healthcare system wants to achieve true value-based care, we need an educated population, higher accountability of staff standards with the ability to send evaluations direct to payers based on specific facts and not emotion, and surveys must include care competency reviews versus only veneer questions of politeness, room appearances, and on time scheduling.
| As the dark side of IVF slowly comes into focus, even more transparency is needed by Pamela Mahoney Tsigdinos, July 27, 2018 |  |
There are pitfalls with IVF that are not discussed. And, this business end of reproduction is more often than not cash only. There are virtually ZERO long term studies regarding what effect-impact freezing, and a host of other ‘things’, that are done to the egg, or sperm, or the embryos that have (or could have) on the child that is produced. This 'miracle of modern medicine' could be good ... or just OK ... or it could be very, very bad. Science has rubbed the lamp and we cannot put the genie back in the bottle. After counseling many women in my career, the great emotional toil let alone the finances are not discussed. The ethical check is also missing regarding instances of doctors using their own sperm such as the Indiana doctor who in 2016 used his own sperm at least 50 times.
As the character Dr. Ian Malcom (played by Jeff Goldblum) said in the 1993 movie Jurassic Park, “Your scientists were so preoccupied with whether they could (create life) that they didn’t stop to think if they should.” by Karen F., (Ret) RN, NP OB & Palliative Care
by Rose Rohloff
The June 29, 2018 BECKER'S Hospital Review article shares the viewpoint "Froedtert CEO Cathy Jacobson: Not every patient needs a primary care physician" (PCP). The article is the perspective from the viewpoint of a health system CEO. The following is a perspective, counterview from patients, the individuals in the population.
The June 29, 2018 BECKER'S Hospital Review article shares the viewpoint "Froedtert CEO Cathy Jacobson: Not every patient needs a primary care physician" (PCP). The article is the perspective from the viewpoint of a health system CEO. The following is a perspective, counterview from patients, the individuals in the population.
In speaking with individuals across the country, spanning several major health systems and states, 100% of the comments and feelings are that health systems are large, top-heavy and more inefficiently run because of their size.
Many people have expressed utter frustration from lack of a good Primary Care Doctor, warranting unnecessary ER visits because a doctor will not call back; the lack of one doctor in charge who would simply LISTEN to them, who knows them - not as personal friends, but with an in-depth professional relationship.
I have been asked several times in various states, "Do you know of any good Primary Care Doctors? I cannot find one." Universally, I am hearing: a gross lack of comprehensive assessments from doctors; clinicians not taking the time to get to know and listen to what is going on, causing the passing through of patients to specialists versus a primary care doctor creating a plan of care and focused tests for getting an actual diagnosis; lack of avoidance for hospital visits with increasing costs that could and should be avoided because conditions allowed to worsen; and doctors simply writing prescriptions for symptoms.
Many people have expressed utter frustration from lack of a good Primary Care Doctor, warranting unnecessary ER visits because a doctor will not call back; the lack of one doctor in charge who would simply LISTEN to them, who knows them - not as personal friends, but with an in-depth professional relationship.
I have been asked several times in various states, "Do you know of any good Primary Care Doctors? I cannot find one." Universally, I am hearing: a gross lack of comprehensive assessments from doctors; clinicians not taking the time to get to know and listen to what is going on, causing the passing through of patients to specialists versus a primary care doctor creating a plan of care and focused tests for getting an actual diagnosis; lack of avoidance for hospital visits with increasing costs that could and should be avoided because conditions allowed to worsen; and doctors simply writing prescriptions for symptoms.
Health systems are relying on data analysis, defining as population health, as Froedtert is quoted, "As we start stratifying our patients into distinct populations based on their health needs." The issue with this premise is that the data is not always clean, and it will never tell the story, the whole story, of the realities going on with the patients. (See I Wish I Had Known stories.)
Her quote continues, "... insight further into consumer driven wants, we are finding that a substantial sector of the population does not want or need a primary care physician relationship. People need primary care but not necessarily a physician relationship." The issue is the primary care physician practices have been acquired by the hospital-health systems, with the biggest complaint from people in the population not being able to find a PCP; and those now under health systems, the doctor only giving 10-15 minutes of time, before passing off to specialists with no plan of care, and/or simply writing another prescription. Many in the public just find it faster, or are being told to just go to the ER. From the perspective of health system CEOs, it would appear primary care is not wanted or needed, which drives up the hospital ER and inpatient business. When actually speaking with individuals across the country, it is the opposite, people complain lack of care coordination, and "the doctor doesn't know me and is not taking the time to listen to me - I want them to actually figure out a diagnosis of what is wrong."
Her quote continues, "... insight further into consumer driven wants, we are finding that a substantial sector of the population does not want or need a primary care physician relationship. People need primary care but not necessarily a physician relationship." The issue is the primary care physician practices have been acquired by the hospital-health systems, with the biggest complaint from people in the population not being able to find a PCP; and those now under health systems, the doctor only giving 10-15 minutes of time, before passing off to specialists with no plan of care, and/or simply writing another prescription. Many in the public just find it faster, or are being told to just go to the ER. From the perspective of health system CEOs, it would appear primary care is not wanted or needed, which drives up the hospital ER and inpatient business. When actually speaking with individuals across the country, it is the opposite, people complain lack of care coordination, and "the doctor doesn't know me and is not taking the time to listen to me - I want them to actually figure out a diagnosis of what is wrong."
by Rose Rohloff
A Memorial Day quote yesterday regarding veterans also exemplifies much of what has happened in healthcare over the last 10 years, regarding the focus on Population Health, meaningful use reporting, value based analysis, big data analytics-claims data, and mergers of health systems with large EMRs, with focus on reporting.
“We are arguing over a statistical analysis. This is the challenge that we face in society today ,,, we are quantifying numbers because it’s easy to look at a number, and it’s not easy to look at the value of a human life. I would say to you today that (losing) one a day, one a year is too many.”
Kyle Reyes, CEO, The Silent Partner Marketing
Kyle Reyes, CEO, The Silent Partner Marketing
When the primary focus is on data (the multiple of numbers/records-statistics), singular records and numbers or outliers are not worth the time and effort of analysts and executives. And yet, they should be as each record is a real patient, a friend, a loved one.
The solution is bringing analysis down to the most base level of management with front line analysis, to coincide with first-hand observation, the voice of the patient & their caregivers/champions, and reducing the ever growing administrative overhead. Bigger is not better for addressing health and care of populations, when the focus is shifted upward with large systems where individuals are lost: Especially when the individual issues are indicative of the core problems that need to be addressed for quality care delivery.
The need for P&P Reviews
The solution is bringing analysis down to the most base level of management with front line analysis, to coincide with first-hand observation, the voice of the patient & their caregivers/champions, and reducing the ever growing administrative overhead. Bigger is not better for addressing health and care of populations, when the focus is shifted upward with large systems where individuals are lost: Especially when the individual issues are indicative of the core problems that need to be addressed for quality care delivery.
The need for P&P Reviews
